Product Information
TOPIRAMATE 25 MG/ML SOLUTION is a generic product labeled by Ascend Laboratories, LLC, priced at $1.0826 per ML under NDC 67877083347. Its NADAC has been published 36 times since Dec 17, 2025.
FDA first approved this application on Oct 31, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/mL
Manufacturer
Ascend Laboratories, LLCNDC
67877083347
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA217795FDA Approved
10/31/2024
TE Code
AB
On Market Since
7/7/2025
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE 25 MG/ML SOLUTION has been published 36 times since Dec 17, 2025, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0826 per ML |
|---|---|
| All-time high | $1.0929 (Jun 10, 2026) |
| All-time low | $1.0667 (Feb 18, 2026) |
| 52-week high | $1.0929 |
| 52-week low | $1.0667 |
| Median price | $1.0837 |
| Average price | $1.0799 |
| Largest weekly change | +1.3% (May 20, 2026) |
| Weeks tracked | 36 |
| Tracking since | Dec 17, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOPIRAMATE 25 MG/ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 25 MG/ML SOLUTION, manufactured by Ascend Laboratories, LLC, is $1.0826 per ML (NDC 67877083347), effective Aug 19, 2026.
How has the price of TOPIRAMATE 25 MG/ML SOLUTION changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE 25 MG/ML SOLUTION has held within roughly two percent of its current level. It has been tracked across 36 weekly CMS publications since Dec 17, 2025.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE 25 MG/ML SOLUTION?
Since Dec 17, 2025, the NADAC for TOPIRAMATE 25 MG/ML SOLUTION has ranged from a low of $1.0667 (Feb 18, 2026) to a high of $1.0929 (Jun 10, 2026), with a median of $1.0837 per ML.
Are there cheaper alternatives to TOPIRAMATE 25 MG/ML SOLUTION?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as TOPIRAMATE 25 MG/ML SOLUTION in a comparable dosage form, but none are currently priced below it.
Who manufactures TOPIRAMATE 25 MG/ML SOLUTION?
TOPIRAMATE 25 MG/ML SOLUTION (NDC 67877083347) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.