Product Information
TOPIRAMATE 25 MG/ML SOLUTION is a generic product labeled by Ascend Laboratories, LLC, priced at $2.0867 per ML under NDC 67877083361. Its NADAC has been published 33 times since Feb 18, 2026.
FDA first approved this application on Oct 31, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/mL
Manufacturer
Ascend Laboratories, LLCNDC
67877083361
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA217795FDA Approved
10/31/2024
TE Code
AB
On Market Since
7/7/2025
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE 25 MG/ML SOLUTION has been published 33 times since Feb 18, 2026, and over the history we have for it it has risen 9.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.0867 per ML |
|---|---|
| All-time high | $2.1184 (Sep 16, 2026) |
| All-time low | $1.9059 (Feb 18, 2026) |
| 52-week high | $2.1184 |
| 52-week low | $1.9059 |
| Median price | $2.0030 |
| Average price | $2.0204 |
| Largest weekly change | +3.5% (Jun 17, 2026) |
| Weeks tracked | 33 |
| Tracking since | Feb 18, 2026 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 48% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Ascend Laboratories, LLC manufacturer profile
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Drug market
TOPIRAMATE market comparison
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TOPIRAMATE 25 MG/ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 25 MG/ML SOLUTION, manufactured by Ascend Laboratories, LLC, is $2.0867 per ML (NDC 67877083361), effective Sep 30, 2026.
How has the price of TOPIRAMATE 25 MG/ML SOLUTION changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE 25 MG/ML SOLUTION has risen 9.5%. It has been tracked across 33 weekly CMS publications since Feb 18, 2026.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE 25 MG/ML SOLUTION?
Since Feb 18, 2026, the NADAC for TOPIRAMATE 25 MG/ML SOLUTION has ranged from a low of $1.9059 (Feb 18, 2026) to a high of $2.1184 (Sep 16, 2026), with a median of $2.0030 per ML.
Are there cheaper alternatives to TOPIRAMATE 25 MG/ML SOLUTION?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 25 MG/ML SOLUTION, is $1.0824 per ML — about 48% below TOPIRAMATE 25 MG/ML SOLUTION.
Who manufactures TOPIRAMATE 25 MG/ML SOLUTION?
TOPIRAMATE 25 MG/ML SOLUTION (NDC 67877083361) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.