Product Information
TOPIRAMATE 25 MG/ML SOLUTION is a generic product labeled by Ascend Laboratories, LLC, priced at $2.1184 per ML under NDC 67877083361. Its NADAC has been published 27 times since Feb 18, 2026.
FDA first approved this application on Oct 31, 2024. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/mL
Manufacturer
Ascend Laboratories, LLCNDC
67877083361
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA217795FDA Approved
10/31/2024
TE Code
AB
On Market Since
7/7/2025
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE 25 MG/ML SOLUTION has been published 27 times since Feb 18, 2026, and over the history we have for it it has risen 11.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.1184 per ML |
|---|---|
| All-time high | $2.1184 (Aug 19, 2026) |
| All-time low | $1.9059 (Feb 18, 2026) |
| 52-week high | $2.1184 |
| 52-week low | $1.9059 |
| Median price | $2.0030 |
| Average price | $2.0010 |
| Largest weekly change | +3.5% (Jun 17, 2026) |
| Weeks tracked | 27 |
| Tracking since | Feb 18, 2026 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 49% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOPIRAMATE 25 MG/ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 25 MG/ML SOLUTION, manufactured by Ascend Laboratories, LLC, is $2.1184 per ML (NDC 67877083361), effective Aug 19, 2026.
How has the price of TOPIRAMATE 25 MG/ML SOLUTION changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE 25 MG/ML SOLUTION has risen 11.1%. It has been tracked across 27 weekly CMS publications since Feb 18, 2026.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE 25 MG/ML SOLUTION?
Since Feb 18, 2026, the NADAC for TOPIRAMATE 25 MG/ML SOLUTION has ranged from a low of $1.9059 (Feb 18, 2026) to a high of $2.1184 (Aug 19, 2026), with a median of $2.0030 per ML.
Are there cheaper alternatives to TOPIRAMATE 25 MG/ML SOLUTION?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 25 MG/ML SOLUTION, is $1.0826 per ML — about 49% below TOPIRAMATE 25 MG/ML SOLUTION.
Who manufactures TOPIRAMATE 25 MG/ML SOLUTION?
TOPIRAMATE 25 MG/ML SOLUTION (NDC 67877083361) is labeled by Ascend Laboratories, LLC, and CMS classifies it as a generic product.