Product Information
GLUMETZA ER 500 MG TABLET is a brand product labeled by Santarus Inc., priced at $49.2115 per EA under NDC 68012000450. Its NADAC has been published 222 times since Aug 8, 2018.
The High Outlier badge above means this manufacturer's average price in the metformin hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
500 mg/1
Manufacturer
Santarus Inc.NDC
68012000450
Classification
Brand
Dosage Form
TABLET, FILM COATED, EXTENDED RELEASE
Route
ORAL
Last Updated
1/22/2025
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
New Drug (NDA)
FDA Application
NDA021748On Market Since
3/20/2018
Pharmacological Classes
Price Statistics
The NADAC for GLUMETZA ER 500 MG TABLET has been published 222 times since Aug 8, 2018, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $49.2115 per EA |
|---|---|
| All-time high | $49.5423 (Apr 10, 2024) |
| All-time low | $49.2115 (Jan 22, 2025) |
| 52-week high | $49.2115 |
| 52-week low | $49.2115 |
| Median price | $49.4465 |
| Average price | $49.4176 |
| Largest weekly change | -0.4% (Apr 17, 2024) |
| Weeks tracked | 222 |
| Tracking since | Aug 8, 2018 |
Generic Alternatives
The matcher finds 7 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 7 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 100% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of GLUMETZA ER 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for GLUMETZA ER 500 MG TABLET, manufactured by Santarus Inc., is $49.2115 per EA (NDC 68012000450), effective Oct 1, 2025.
How has the price of GLUMETZA ER 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for GLUMETZA ER 500 MG TABLET has held within roughly two percent of its current level. It has been tracked across 222 weekly CMS publications since Aug 8, 2018.
What are the highest and lowest recorded NADAC prices for GLUMETZA ER 500 MG TABLET?
Since Aug 8, 2018, the NADAC for GLUMETZA ER 500 MG TABLET has ranged from a low of $49.2115 (Jan 22, 2025) to a high of $49.5423 (Apr 10, 2024), with a median of $49.4465 per EA.
Are there cheaper alternatives to GLUMETZA ER 500 MG TABLET?
Yes. 7 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0140 per EA — about 100% below GLUMETZA ER 500 MG TABLET.
Who manufactures GLUMETZA ER 500 MG TABLET?
GLUMETZA ER 500 MG TABLET (NDC 68012000450) is labeled by Santarus Inc., and CMS classifies it as a brand product.
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