Product Information
METFORMIN HCL ER 500 MG TABLET is a generic product labeled by Leading Pharma, LLC, priced at $0.0288 per EA under NDC 69315041005. Its NADAC has been published 52 times since Aug 27, 2025.
FDA first approved this application on Jan 18, 2012. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Leading Pharma, LLCNDC
69315041005
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA201991FDA Approved
1/18/2012
TE Code
AB1
On Market Since
5/1/2025
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN HCL ER 500 MG TABLET has been published 52 times since Aug 27, 2025, and over the history we have for it it has declined 3.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0288 per EA |
|---|---|
| All-time high | $0.0299 (Jun 10, 2026) |
| All-time low | $0.0288 (Aug 19, 2026) |
| 52-week high | $0.0299 |
| 52-week low | $0.0288 |
| Median price | $0.0294 |
| Average price | $0.0295 |
| Largest weekly change | -2.2% (Feb 18, 2026) |
| Weeks tracked | 52 |
| Tracking since | Aug 27, 2025 |
Generic Alternatives
The matcher finds 7 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 51% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METFORMIN HCL ER 500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN HCL ER 500 MG TABLET, manufactured by Leading Pharma, LLC, is $0.0288 per EA (NDC 69315041005), effective Aug 19, 2026.
How has the price of METFORMIN HCL ER 500 MG TABLET changed over time?
Over the history we have for it, the NADAC for METFORMIN HCL ER 500 MG TABLET has declined 3.1%. It has been tracked across 52 weekly CMS publications since Aug 27, 2025.
What are the highest and lowest recorded NADAC prices for METFORMIN HCL ER 500 MG TABLET?
Since Aug 27, 2025, the NADAC for METFORMIN HCL ER 500 MG TABLET has ranged from a low of $0.0288 (Aug 19, 2026) to a high of $0.0299 (Jun 10, 2026), with a median of $0.0294 per EA.
Are there cheaper alternatives to METFORMIN HCL ER 500 MG TABLET?
Yes. 7 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0142 per EA — about 51% below METFORMIN HCL ER 500 MG TABLET.
Who manufactures METFORMIN HCL ER 500 MG TABLET?
METFORMIN HCL ER 500 MG TABLET (NDC 69315041005) is labeled by Leading Pharma, LLC, and CMS classifies it as a generic product.