Product Information
METFORMIN ER 500 MG OSMOTIC TB is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.1383 per EA under NDC 68180033607. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Jun 29, 2011. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500 mg/1
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180033607
Classification
Generic
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METFORMIN HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA090692FDA Approved
6/29/2011
TE Code
AB2
On Market Since
9/30/2011
Pharmacological Classes
Price Statistics
The NADAC for METFORMIN ER 500 MG OSMOTIC TB has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 95.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1383 per EA |
|---|---|
| All-time high | $7.2751 (May 11, 2016) |
| All-time low | $0.1017 (Apr 22, 2026) |
| 52-week high | $0.1722 |
| 52-week low | $0.1017 |
| Median price | $2.1184 |
| Average price | $2.2848 |
| Largest weekly change | +170.5% (Feb 17, 2016) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 20 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 90% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of METFORMIN ER 500 MG OSMOTIC TB?
The current National Average Drug Acquisition Cost (NADAC) for METFORMIN ER 500 MG OSMOTIC TB, manufactured by Lupin Pharmaceuticals Inc., is $0.1383 per EA (NDC 68180033607), effective Aug 19, 2026.
How has the price of METFORMIN ER 500 MG OSMOTIC TB changed over time?
Over the history we have for it, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has declined 95.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METFORMIN ER 500 MG OSMOTIC TB?
Since Nov 28, 2013, the NADAC for METFORMIN ER 500 MG OSMOTIC TB has ranged from a low of $0.1017 (Apr 22, 2026) to a high of $7.2751 (May 11, 2016), with a median of $2.1184 per EA.
Are there cheaper alternatives to METFORMIN ER 500 MG OSMOTIC TB?
Yes. 20 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METFORMIN HCL 500 MG TABLET, is $0.0142 per EA — about 90% below METFORMIN ER 500 MG OSMOTIC TB.
Who manufactures METFORMIN ER 500 MG OSMOTIC TB?
METFORMIN ER 500 MG OSMOTIC TB (NDC 68180033607) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.