Product Information
DESOXIMETASONE 0.25% SPRAY is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.5991 per ML under NDC 68180094433. Its NADAC has been published 249 times since May 22, 2019.
FDA first approved this application on Mar 16, 2018. Its Orange Book therapeutic-equivalence code is AT.
Strength
2.5 mg/mL
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180094433
Classification
Generic
Dosage Form
SPRAY
Route
TOPICAL
Effective Date
2/18/2026
Active Ingredients
DESOXIMETASONEApproval Type
Generic (ANDA)
FDA Application
ANDA208124FDA Approved
3/16/2018
TE Code
AT
On Market Since
7/20/2018
Pharmacological Classes
Price Statistics
The NADAC for DESOXIMETASONE 0.25% SPRAY has been published 249 times since May 22, 2019, and over the history we have for it it has declined 51.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.5991 per ML |
|---|---|
| All-time high | $1.4433 (Jun 14, 2023) |
| All-time low | $0.5991 (Feb 18, 2026) |
| 52-week high | $0.7642 |
| 52-week low | $0.5991 |
| Median price | $1.2295 |
| Average price | $1.1291 |
| Largest weekly change | -32.6% (Apr 17, 2024) |
| Weeks tracked | 249 |
| Tracking since | May 22, 2019 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-21.6%
3Y
-58.5%
5Y
-53.3%
All
-51.3%
Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Lupin Pharmaceuticals Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Desoximetasone market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DESOXIMETASONE 0.25% SPRAY?
The current National Average Drug Acquisition Cost (NADAC) for DESOXIMETASONE 0.25% SPRAY, manufactured by Lupin Pharmaceuticals Inc., is $0.5991 per ML (NDC 68180094433), effective Feb 18, 2026.
How has the price of DESOXIMETASONE 0.25% SPRAY changed over time?
Over the history we have for it, the NADAC for DESOXIMETASONE 0.25% SPRAY has declined 51.3%. It has been tracked across 249 weekly CMS publications since May 22, 2019.
What are the highest and lowest recorded NADAC prices for DESOXIMETASONE 0.25% SPRAY?
Since May 22, 2019, the NADAC for DESOXIMETASONE 0.25% SPRAY has ranged from a low of $0.5991 (Feb 18, 2026) to a high of $1.4433 (Jun 14, 2023), with a median of $1.2295 per ML.
Are there cheaper alternatives to DESOXIMETASONE 0.25% SPRAY?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESOXIMETASONE 0.25% SPRAY, is $0.5634 per ML — about 6% below DESOXIMETASONE 0.25% SPRAY.
Who manufactures DESOXIMETASONE 0.25% SPRAY?
DESOXIMETASONE 0.25% SPRAY (NDC 68180094433) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.