Product Information

DESOXIMETASONE 0.25% SPRAY is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.5991 per ML under NDC 68180094433. Its NADAC has been published 249 times since May 22, 2019.

FDA first approved this application on Mar 16, 2018. Its Orange Book therapeutic-equivalence code is AT.

DESOXIMETASONE 0.25% SPRAY

Desoximetasone
$0.5991per ML

Strength

2.5 mg/mL

NDC

68180094433

Classification

Generic

Dosage Form

SPRAY

Route

TOPICAL

Effective Date

2/18/2026

Active Ingredients

DESOXIMETASONE

Approval Type

Generic (ANDA)

FDA Application

ANDA208124

FDA Approved

3/16/2018

TE Code

AT

On Market Since

7/20/2018

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for DESOXIMETASONE 0.25% SPRAY has been published 249 times since May 22, 2019, and over the history we have for it it has declined 51.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.5991 per ML
All-time high$1.4433 (Jun 14, 2023)
All-time low$0.5991 (Feb 18, 2026)
52-week high$0.9186
52-week low$0.5991
Median price$1.2295
Average price$1.1291
Largest weekly change-32.6% (Apr 17, 2024)
Weeks tracked249
Tracking sinceMay 22, 2019

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-34.8%

3Y

-58.5%

5Y

-53.3%

All

-51.3%

Last surveyed Feb 18, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 6% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 6%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of DESOXIMETASONE 0.25% SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for DESOXIMETASONE 0.25% SPRAY, manufactured by Lupin Pharmaceuticals Inc., is $0.5991 per ML (NDC 68180094433), effective Feb 18, 2026.

How has the price of DESOXIMETASONE 0.25% SPRAY changed over time?

Over the history we have for it, the NADAC for DESOXIMETASONE 0.25% SPRAY has declined 51.3%. It has been tracked across 249 weekly CMS publications since May 22, 2019.

What are the highest and lowest recorded NADAC prices for DESOXIMETASONE 0.25% SPRAY?

Since May 22, 2019, the NADAC for DESOXIMETASONE 0.25% SPRAY has ranged from a low of $0.5991 (Feb 18, 2026) to a high of $1.4433 (Jun 14, 2023), with a median of $1.2295 per ML.

Are there cheaper alternatives to DESOXIMETASONE 0.25% SPRAY?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESOXIMETASONE 0.25% SPRAY, is $0.5634 per ML — about 6% below DESOXIMETASONE 0.25% SPRAY.

Who manufactures DESOXIMETASONE 0.25% SPRAY?

DESOXIMETASONE 0.25% SPRAY (NDC 68180094433) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.