Product Information
DESOXIMETASONE 0.25% CREAM is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.3979 per GM under NDC 68180095001. Its NADAC has been published 477 times since Aug 16, 2017.
FDA first approved this application on Jan 9, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/g
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180095001
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
DESOXIMETASONEApproval Type
Generic (ANDA)
FDA Application
ANDA208164FDA Approved
1/9/2017
TE Code
AB
On Market Since
6/20/2017
Pharmacological Classes
Price Statistics
The NADAC for DESOXIMETASONE 0.25% CREAM has been published 477 times since Aug 16, 2017, and over the history we have for it it has declined 71.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3979 per GM |
|---|---|
| All-time high | $1.5594 (May 16, 2018) |
| All-time low | $0.3770 (Aug 20, 2025) |
| 52-week high | $0.4846 |
| 52-week low | $0.3780 |
| Median price | $0.8972 |
| Average price | $0.8872 |
| Largest weekly change | +108.7% (Mar 18, 2020) |
| Weeks tracked | 477 |
| Tracking since | Aug 16, 2017 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 19% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Lupin Pharmaceuticals Inc. manufacturer profile
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Drug market
Desoximetasone market comparison
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Therapeutic class
Corticosteroid class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of DESOXIMETASONE 0.25% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESOXIMETASONE 0.25% CREAM, manufactured by Lupin Pharmaceuticals Inc., is $0.3979 per GM (NDC 68180095001), effective Sep 30, 2026.
How has the price of DESOXIMETASONE 0.25% CREAM changed over time?
Over the history we have for it, the NADAC for DESOXIMETASONE 0.25% CREAM has declined 71.7%. It has been tracked across 477 weekly CMS publications since Aug 16, 2017.
What are the highest and lowest recorded NADAC prices for DESOXIMETASONE 0.25% CREAM?
Since Aug 16, 2017, the NADAC for DESOXIMETASONE 0.25% CREAM has ranged from a low of $0.3770 (Aug 20, 2025) to a high of $1.5594 (May 16, 2018), with a median of $0.8972 per GM.
Are there cheaper alternatives to DESOXIMETASONE 0.25% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESOXIMETASONE 0.25% CREAM, is $0.3227 per GM — about 19% below DESOXIMETASONE 0.25% CREAM.
Who manufactures DESOXIMETASONE 0.25% CREAM?
DESOXIMETASONE 0.25% CREAM (NDC 68180095001) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.