Product Information
DESOXIMETASONE 0.25% CREAM is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.3847 per GM under NDC 68180095001. Its NADAC has been published 471 times since Aug 16, 2017.
FDA first approved this application on Jan 9, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
2.5 mg/g
Manufacturer
Lupin Pharmaceuticals Inc.NDC
68180095001
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
8/19/2026
Active Ingredients
DESOXIMETASONEApproval Type
Generic (ANDA)
FDA Application
ANDA208164FDA Approved
1/9/2017
TE Code
AB
On Market Since
6/20/2017
Pharmacological Classes
Price Statistics
The NADAC for DESOXIMETASONE 0.25% CREAM has been published 471 times since Aug 16, 2017, and over the history we have for it it has declined 72.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3847 per GM |
|---|---|
| All-time high | $1.5594 (May 16, 2018) |
| All-time low | $0.3770 (Aug 20, 2025) |
| 52-week high | $0.4846 |
| 52-week low | $0.3770 |
| Median price | $0.8972 |
| Average price | $0.8935 |
| Largest weekly change | +108.7% (Mar 18, 2020) |
| Weeks tracked | 471 |
| Tracking since | Aug 16, 2017 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 18% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DESOXIMETASONE 0.25% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for DESOXIMETASONE 0.25% CREAM, manufactured by Lupin Pharmaceuticals Inc., is $0.3847 per GM (NDC 68180095001), effective Aug 19, 2026.
How has the price of DESOXIMETASONE 0.25% CREAM changed over time?
Over the history we have for it, the NADAC for DESOXIMETASONE 0.25% CREAM has declined 72.7%. It has been tracked across 471 weekly CMS publications since Aug 16, 2017.
What are the highest and lowest recorded NADAC prices for DESOXIMETASONE 0.25% CREAM?
Since Aug 16, 2017, the NADAC for DESOXIMETASONE 0.25% CREAM has ranged from a low of $0.3770 (Aug 20, 2025) to a high of $1.5594 (May 16, 2018), with a median of $0.8972 per GM.
Are there cheaper alternatives to DESOXIMETASONE 0.25% CREAM?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, DESOXIMETASONE 0.25% CREAM, is $0.3174 per GM — about 18% below DESOXIMETASONE 0.25% CREAM.
Who manufactures DESOXIMETASONE 0.25% CREAM?
DESOXIMETASONE 0.25% CREAM (NDC 68180095001) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.