Product Information

FLUOXETINE HCL 20 MG TABLET is a generic product labeled by Lupin Pharmaceuticals Inc., priced at $0.0883 per EA under NDC 68180099901. Its NADAC has been published 319 times since Oct 16, 2019.

FDA first approved this application on Apr 15, 2019. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

FLUOXETINE HCL 20 MG TABLET

Fluoxetine Hydrochloride
$0.0883per EA

Strength

20 mg/1

NDC

68180099901

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

11/19/2025

Active Ingredients

FLUOXETINE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA211653

FDA Approved

4/15/2019

TE Code

AB

On Market Since

8/7/2019

Pharmacological Classes

Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for FLUOXETINE HCL 20 MG TABLET has been published 319 times since Oct 16, 2019, and over the history we have for it it has declined 86.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0883 per EA
All-time high$0.6808 (Feb 12, 2020)
All-time low$0.0653 (Nov 20, 2024)
52-week high$0.1237
52-week low$0.0883
Median price$0.2104
Average price$0.2478
Largest weekly change+51.8% (Nov 22, 2023)
Weeks tracked319
Tracking sinceOct 16, 2019

Price History

1W

N/A

1M

N/A

3M

N/A

6M

N/A

1Y

-28.6%

3Y

-38.3%

5Y

-64.1%

All

-86.2%

Last surveyed Nov 19, 2025 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of FLUOXETINE HCL 20 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for FLUOXETINE HCL 20 MG TABLET, manufactured by Lupin Pharmaceuticals Inc., is $0.0883 per EA (NDC 68180099901), effective Nov 19, 2025.

How has the price of FLUOXETINE HCL 20 MG TABLET changed over time?

Over the history we have for it, the NADAC for FLUOXETINE HCL 20 MG TABLET has declined 86.2%. It has been tracked across 319 weekly CMS publications since Oct 16, 2019.

What are the highest and lowest recorded NADAC prices for FLUOXETINE HCL 20 MG TABLET?

Since Oct 16, 2019, the NADAC for FLUOXETINE HCL 20 MG TABLET has ranged from a low of $0.0653 (Nov 20, 2024) to a high of $0.6808 (Feb 12, 2020), with a median of $0.2104 per EA.

Are there cheaper alternatives to FLUOXETINE HCL 20 MG TABLET?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as FLUOXETINE HCL 20 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures FLUOXETINE HCL 20 MG TABLET?

FLUOXETINE HCL 20 MG TABLET (NDC 68180099901) is labeled by Lupin Pharmaceuticals Inc., and CMS classifies it as a generic product.