Product Information

METRONIDAZOLE TOPICAL 1% GEL is a generic product labeled by Mayne Pharma, priced at $0.6209 per GM under NDC 68308066360. Its NADAC has been published 55 times since Aug 6, 2025.

FDA first approved this application on Jun 30, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METRONIDAZOLE TOPICAL 1% GEL

metronidazole
$0.6209per GM

Strength

10 mg/g

Manufacturer

Mayne Pharma

NDC

68308066360

Classification

Generic

Dosage Form

GEL

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

METRONIDAZOLE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA021789

FDA Approved

6/30/2005

TE Code

AB

On Market Since

11/10/2023

Pharmacological Classes

Price Statistics

The NADAC for METRONIDAZOLE TOPICAL 1% GEL has been published 55 times since Aug 6, 2025, and over the history we have for it it has declined 20.9%. The table below summarizes its recorded NADAC range and movement.

Current price$0.6209 per GM
All-time high$0.8011 (Oct 15, 2025)
All-time low$0.6209 (Aug 19, 2026)
52-week high$0.8011
52-week low$0.6209
Median price$0.6840
Average price$0.7095
Largest weekly change-5.4% (Dec 17, 2025)
Weeks tracked55
Tracking sinceAug 6, 2025

Price History

1W

-2.4%

1M

-2.4%

3M

-9.2%

6M

-7.7%

1Y

-22.0%

3Y

N/A

5Y

N/A

All

-20.9%

Generic Alternatives

The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 9% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of METRONIDAZOLE TOPICAL 1% GEL?

The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE TOPICAL 1% GEL, manufactured by Mayne Pharma, is $0.6209 per GM (NDC 68308066360), effective Aug 19, 2026.

How has the price of METRONIDAZOLE TOPICAL 1% GEL changed over time?

Over the history we have for it, the NADAC for METRONIDAZOLE TOPICAL 1% GEL has declined 20.9%. It has been tracked across 55 weekly CMS publications since Aug 6, 2025.

What are the highest and lowest recorded NADAC prices for METRONIDAZOLE TOPICAL 1% GEL?

Since Aug 6, 2025, the NADAC for METRONIDAZOLE TOPICAL 1% GEL has ranged from a low of $0.6209 (Aug 19, 2026) to a high of $0.8011 (Oct 15, 2025), with a median of $0.6840 per GM.

Are there cheaper alternatives to METRONIDAZOLE TOPICAL 1% GEL?

Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METRONIDAZOLE TOP 1% GEL PUMP, is $0.5654 per GM — about 9% below METRONIDAZOLE TOPICAL 1% GEL.

Who manufactures METRONIDAZOLE TOPICAL 1% GEL?

METRONIDAZOLE TOPICAL 1% GEL (NDC 68308066360) is labeled by Mayne Pharma, and CMS classifies it as a generic product.