Product Information
METRONIDAZOLE TOPICAL 1% GEL is a generic product labeled by Mayne Pharma, priced at $0.6210 per GM under NDC 68308066360. Its NADAC has been published 61 times since Aug 6, 2025.
FDA first approved this application on Jun 30, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
10 mg/g
Manufacturer
Mayne PharmaNDC
68308066360
Classification
Generic
Dosage Form
GEL
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
METRONIDAZOLEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021789FDA Approved
6/30/2005
TE Code
AB
On Market Since
11/10/2023
Pharmacological Classes
Price Statistics
The NADAC for METRONIDAZOLE TOPICAL 1% GEL has been published 61 times since Aug 6, 2025, and over the history we have for it it has declined 20.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.6210 per GM |
|---|---|
| All-time high | $0.8011 (Oct 15, 2025) |
| All-time low | $0.6209 (Aug 19, 2026) |
| 52-week high | $0.8011 |
| 52-week low | $0.6209 |
| Median price | $0.6838 |
| Average price | $0.7008 |
| Largest weekly change | -5.4% (Dec 17, 2025) |
| Weeks tracked | 61 |
| Tracking since | Aug 6, 2025 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 13% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Mayne Pharma manufacturer profile
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Therapeutic class
Nitroimidazole Antimicrobial class view
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Trend hub
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METRONIDAZOLE TOPICAL 1% GEL?
The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE TOPICAL 1% GEL, manufactured by Mayne Pharma, is $0.6210 per GM (NDC 68308066360), effective Sep 30, 2026.
How has the price of METRONIDAZOLE TOPICAL 1% GEL changed over time?
Over the history we have for it, the NADAC for METRONIDAZOLE TOPICAL 1% GEL has declined 20.9%. It has been tracked across 61 weekly CMS publications since Aug 6, 2025.
What are the highest and lowest recorded NADAC prices for METRONIDAZOLE TOPICAL 1% GEL?
Since Aug 6, 2025, the NADAC for METRONIDAZOLE TOPICAL 1% GEL has ranged from a low of $0.6209 (Aug 19, 2026) to a high of $0.8011 (Oct 15, 2025), with a median of $0.6838 per GM.
Are there cheaper alternatives to METRONIDAZOLE TOPICAL 1% GEL?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METRONIDAZOLE TOP 1% GEL PUMP, is $0.5399 per GM — about 13% below METRONIDAZOLE TOPICAL 1% GEL.
Who manufactures METRONIDAZOLE TOPICAL 1% GEL?
METRONIDAZOLE TOPICAL 1% GEL (NDC 68308066360) is labeled by Mayne Pharma, and CMS classifies it as a generic product.