Product Information

METRONIDAZOLE 0.75% CREAM is a generic product labeled by Mayne Pharma, priced at $0.2684 per GM under NDC 68308071145. Its NADAC has been published 60 times since Jul 2, 2025.

FDA first approved this application on Sep 20, 1995. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

METRONIDAZOLE 0.75% CREAM

METRONIDAZOLE
$0.2684per GM

Strength

7.5 mg/g

Manufacturer

Mayne Pharma

NDC

68308071145

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

METRONIDAZOLE

Approval Type

Authorized Generic (NDA)

FDA Application

NDA020531

FDA Approved

9/20/1995

TE Code

AB

On Market Since

5/19/2025

Pharmacological Classes

Price Statistics

The NADAC for METRONIDAZOLE 0.75% CREAM has been published 60 times since Jul 2, 2025, and over the history we have for it it has declined 24.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.2684 per GM
All-time high$0.3648 (Aug 13, 2025)
All-time low$0.2684 (Aug 19, 2026)
52-week high$0.3635
52-week low$0.2684
Median price$0.2927
Average price$0.3073
Largest weekly change-11.8% (Sep 17, 2025)
Weeks tracked60
Tracking sinceJul 2, 2025

Price History

1W

-2.1%

1M

-2.1%

3M

-8.3%

6M

-9.1%

1Y

-26.2%

3Y

N/A

5Y

N/A

All

-24.2%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of METRONIDAZOLE 0.75% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE 0.75% CREAM, manufactured by Mayne Pharma, is $0.2684 per GM (NDC 68308071145), effective Aug 19, 2026.

How has the price of METRONIDAZOLE 0.75% CREAM changed over time?

Over the history we have for it, the NADAC for METRONIDAZOLE 0.75% CREAM has declined 24.2%. It has been tracked across 60 weekly CMS publications since Jul 2, 2025.

What are the highest and lowest recorded NADAC prices for METRONIDAZOLE 0.75% CREAM?

Since Jul 2, 2025, the NADAC for METRONIDAZOLE 0.75% CREAM has ranged from a low of $0.2684 (Aug 19, 2026) to a high of $0.3648 (Aug 13, 2025), with a median of $0.2927 per GM.

Are there cheaper alternatives to METRONIDAZOLE 0.75% CREAM?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METRONIDAZOLE 0.75% CREAM in a comparable dosage form, but none are currently priced below it.

Who manufactures METRONIDAZOLE 0.75% CREAM?

METRONIDAZOLE 0.75% CREAM (NDC 68308071145) is labeled by Mayne Pharma, and CMS classifies it as a generic product.