Product Information
METRONIDAZOLE 0.75% CREAM is a generic product labeled by Mayne Pharma, priced at $0.2571 per GM under NDC 68308071145. Its NADAC has been published 66 times since Jul 2, 2025.
FDA first approved this application on Sep 20, 1995. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
7.5 mg/g
Manufacturer
Mayne PharmaNDC
68308071145
Classification
Generic
Dosage Form
CREAM
Route
TOPICAL
Effective Date
9/23/2026
Active Ingredients
METRONIDAZOLEApproval Type
Authorized Generic (NDA)
FDA Application
NDA020531FDA Approved
9/20/1995
TE Code
AB
On Market Since
5/19/2025
Pharmacological Classes
Price Statistics
The NADAC for METRONIDAZOLE 0.75% CREAM has been published 66 times since Jul 2, 2025, and over the history we have for it it has declined 27.4%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2571 per GM |
|---|---|
| All-time high | $0.3648 (Aug 13, 2025) |
| All-time low | $0.2571 (Sep 23, 2026) |
| 52-week high | $0.3207 |
| 52-week low | $0.2571 |
| Median price | $0.2925 |
| Average price | $0.3035 |
| Largest weekly change | -11.8% (Sep 17, 2025) |
| Weeks tracked | 66 |
| Tracking since | Jul 2, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Mayne Pharma manufacturer profile
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Drug market
METRONIDAZOLE market comparison
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Therapeutic class
Nitroimidazole Antimicrobial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METRONIDAZOLE 0.75% CREAM?
The current National Average Drug Acquisition Cost (NADAC) for METRONIDAZOLE 0.75% CREAM, manufactured by Mayne Pharma, is $0.2571 per GM (NDC 68308071145), effective Sep 30, 2026.
How has the price of METRONIDAZOLE 0.75% CREAM changed over time?
Over the history we have for it, the NADAC for METRONIDAZOLE 0.75% CREAM has declined 27.4%. It has been tracked across 66 weekly CMS publications since Jul 2, 2025.
What are the highest and lowest recorded NADAC prices for METRONIDAZOLE 0.75% CREAM?
Since Jul 2, 2025, the NADAC for METRONIDAZOLE 0.75% CREAM has ranged from a low of $0.2571 (Sep 23, 2026) to a high of $0.3648 (Aug 13, 2025), with a median of $0.2925 per GM.
Are there cheaper alternatives to METRONIDAZOLE 0.75% CREAM?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as METRONIDAZOLE 0.75% CREAM in a comparable dosage form, but none are currently priced below it.
Who manufactures METRONIDAZOLE 0.75% CREAM?
METRONIDAZOLE 0.75% CREAM (NDC 68308071145) is labeled by Mayne Pharma, and CMS classifies it as a generic product.