Product Information
TRAZODONE 300 MG TABLET is a generic product labeled by Zydus Pharmaceuticals (USA) Inc., priced at $0.4977 per EA under NDC 68382080801. Its NADAC has been published 444 times since Apr 4, 2018.
FDA first approved this application on Oct 10, 2017. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
300 mg/1
Manufacturer
Zydus Pharmaceuticals (USA) Inc.NDC
68382080801
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TRAZODONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA205253FDA Approved
10/10/2017
TE Code
AB
On Market Since
12/11/2017
Pharmacological Classes
Price Statistics
The NADAC for TRAZODONE 300 MG TABLET has been published 444 times since Apr 4, 2018, and over the history we have for it it has declined 78.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.4977 per EA |
|---|---|
| All-time high | $2.5564 (May 16, 2018) |
| All-time low | $0.4977 (Sep 23, 2026) |
| 52-week high | $0.5876 |
| 52-week low | $0.4977 |
| Median price | $1.5367 |
| Average price | $1.4866 |
| Largest weekly change | +68.9% (Aug 21, 2024) |
| Weeks tracked | 444 |
| Tracking since | Apr 4, 2018 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Zydus Pharmaceuticals (USA) Inc. manufacturer profile
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Drug market
Trazodone Hydrochloride market comparison
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Therapeutic class
Serotonin Reuptake Inhibitor class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TRAZODONE 300 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TRAZODONE 300 MG TABLET, manufactured by Zydus Pharmaceuticals (USA) Inc., is $0.4977 per EA (NDC 68382080801), effective Sep 30, 2026.
How has the price of TRAZODONE 300 MG TABLET changed over time?
Over the history we have for it, the NADAC for TRAZODONE 300 MG TABLET has declined 78.5%. It has been tracked across 444 weekly CMS publications since Apr 4, 2018.
What are the highest and lowest recorded NADAC prices for TRAZODONE 300 MG TABLET?
Since Apr 4, 2018, the NADAC for TRAZODONE 300 MG TABLET has ranged from a low of $0.4977 (Sep 23, 2026) to a high of $2.5564 (May 16, 2018), with a median of $1.5367 per EA.
Are there cheaper alternatives to TRAZODONE 300 MG TABLET?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TRAZODONE 300 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures TRAZODONE 300 MG TABLET?
TRAZODONE 300 MG TABLET (NDC 68382080801) is labeled by Zydus Pharmaceuticals (USA) Inc., and CMS classifies it as a generic product.