Product Information

TOPIRAMATE 100 MG TABLET is a generic product labeled by Glenmark Pharmaceuticals Inc., USA, priced at $0.0567 per EA under NDC 68462010905. Its NADAC has been published 305 times since Dec 2, 2020.

FDA first approved this application on Mar 27, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TOPIRAMATE 100 MG TABLET

Topiramate
$0.0567per EA

Strength

100 mg/1

NDC

68462010905

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

9/23/2026

Active Ingredients

TOPIRAMATE

Approval Type

Generic (ANDA)

FDA Application

ANDA077627

FDA Approved

3/27/2009

TE Code

AB

On Market Since

3/27/2009

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for TOPIRAMATE 100 MG TABLET has been published 305 times since Dec 2, 2020, and over the history we have for it it has declined 20.3%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0567 per EA
All-time high$0.0711 (Dec 16, 2020)
All-time low$0.0486 (Nov 20, 2024)
52-week high$0.0628
52-week low$0.0550
Median price$0.0642
Average price$0.0636
Largest weekly change+33.1% (Aug 21, 2024)
Weeks tracked305
Tracking sinceDec 2, 2020

Price History

1W

0.0%

1M

+3.0%

3M

-2.2%

6M

-3.5%

1Y

-9.7%

3Y

-15.6%

5Y

-15.4%

All

-20.3%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 3% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of TOPIRAMATE 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 100 MG TABLET, manufactured by Glenmark Pharmaceuticals Inc., USA, is $0.0567 per EA (NDC 68462010905), effective Sep 30, 2026.

How has the price of TOPIRAMATE 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for TOPIRAMATE 100 MG TABLET has declined 20.3%. It has been tracked across 305 weekly CMS publications since Dec 2, 2020.

What are the highest and lowest recorded NADAC prices for TOPIRAMATE 100 MG TABLET?

Since Dec 2, 2020, the NADAC for TOPIRAMATE 100 MG TABLET has ranged from a low of $0.0486 (Nov 20, 2024) to a high of $0.0711 (Dec 16, 2020), with a median of $0.0642 per EA.

Are there cheaper alternatives to TOPIRAMATE 100 MG TABLET?

Yes. 6 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, TOPIRAMATE 100 MG TABLET, is $0.0550 per EA — about 3% below TOPIRAMATE 100 MG TABLET.

Who manufactures TOPIRAMATE 100 MG TABLET?

TOPIRAMATE 100 MG TABLET (NDC 68462010905) is labeled by Glenmark Pharmaceuticals Inc., USA, and CMS classifies it as a generic product.