Product Information
LOPERAMIDE-SIMETH 2-125 MG TAB is a generic product labeled by Camber Consumer Care, priced at $0.2857 per EA under NDC 69230032512. Its NADAC has been published 260 times since Oct 13, 2021.
FDA first approved this application on Jun 17, 2021.
Strength
125; 2 mg/1; mg/1
Manufacturer
Camber Consumer CareNDC
69230032512
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
DIMETHICONE; LOPERAMIDE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA211438FDA Approved
6/17/2021
On Market Since
6/17/2021
Pharmacological Classes
Price Statistics
The NADAC for LOPERAMIDE-SIMETH 2-125 MG TAB has been published 260 times since Oct 13, 2021, and over the history we have for it it has risen 5.7%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2857 per EA |
|---|---|
| All-time high | $0.3621 (Sep 13, 2023) |
| All-time low | $0.2638 (Jun 18, 2025) |
| 52-week high | $0.3073 |
| 52-week low | $0.2857 |
| Median price | $0.2903 |
| Average price | $0.2920 |
| Largest weekly change | +21.9% (Aug 23, 2023) |
| Weeks tracked | 260 |
| Tracking since | Oct 13, 2021 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Camber Consumer Care manufacturer profile
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Drug market
Loperamide Hydrochloride and Simethicone market comparison
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Therapeutic class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LOPERAMIDE-SIMETH 2-125 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LOPERAMIDE-SIMETH 2-125 MG TAB, manufactured by Camber Consumer Care, is $0.2857 per EA (NDC 69230032512), effective Sep 30, 2026.
How has the price of LOPERAMIDE-SIMETH 2-125 MG TAB changed over time?
Over the history we have for it, the NADAC for LOPERAMIDE-SIMETH 2-125 MG TAB has risen 5.7%. It has been tracked across 260 weekly CMS publications since Oct 13, 2021.
What are the highest and lowest recorded NADAC prices for LOPERAMIDE-SIMETH 2-125 MG TAB?
Since Oct 13, 2021, the NADAC for LOPERAMIDE-SIMETH 2-125 MG TAB has ranged from a low of $0.2638 (Jun 18, 2025) to a high of $0.3621 (Sep 13, 2023), with a median of $0.2903 per EA.
Are there cheaper alternatives to LOPERAMIDE-SIMETH 2-125 MG TAB?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as LOPERAMIDE-SIMETH 2-125 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LOPERAMIDE-SIMETH 2-125 MG TAB?
LOPERAMIDE-SIMETH 2-125 MG TAB (NDC 69230032512) is labeled by Camber Consumer Care, and CMS classifies it as a generic product.