Product Information
TOPIRAMATE ER 50 MG SPRINKL CAP is a generic product labeled by Vitruvias Therapeutics Inc., priced at $3.1462 per EA under NDC 69680017830. Its NADAC has been published 65 times since Jul 9, 2025.
FDA first approved this application on Nov 5, 2024. Its Orange Book therapeutic-equivalence code is AB2 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
50 mg/1
Manufacturer
Vitruvias Therapeutics Inc.NDC
69680017830
Classification
Generic
Dosage Form
CAPSULE, EXTENDED RELEASE
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
TOPIRAMATEApproval Type
Generic (ANDA)
FDA Application
ANDA215638FDA Approved
11/5/2024
TE Code
AB2
On Market Since
4/7/2025
Pharmacological Classes
Price Statistics
The NADAC for TOPIRAMATE ER 50 MG SPRINKL CAP has been published 65 times since Jul 9, 2025, and over the history we have for it it has declined 39.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $3.1462 per EA |
|---|---|
| All-time high | $5.5824 (Feb 11, 2026) |
| All-time low | $3.1462 (Sep 23, 2026) |
| 52-week high | $5.5824 |
| 52-week low | $3.1462 |
| Median price | $4.9252 |
| Average price | $4.5287 |
| Largest weekly change | -14.8% (Apr 22, 2026) |
| Weeks tracked | 65 |
| Tracking since | Jul 9, 2025 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Vitruvias Therapeutics Inc. manufacturer profile
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Drug market
Topiramate market comparison
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Trend hub
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of TOPIRAMATE ER 50 MG SPRINKL CAP?
The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE ER 50 MG SPRINKL CAP, manufactured by Vitruvias Therapeutics Inc., is $3.1462 per EA (NDC 69680017830), effective Sep 30, 2026.
How has the price of TOPIRAMATE ER 50 MG SPRINKL CAP changed over time?
Over the history we have for it, the NADAC for TOPIRAMATE ER 50 MG SPRINKL CAP has declined 39.8%. It has been tracked across 65 weekly CMS publications since Jul 9, 2025.
What are the highest and lowest recorded NADAC prices for TOPIRAMATE ER 50 MG SPRINKL CAP?
Since Jul 9, 2025, the NADAC for TOPIRAMATE ER 50 MG SPRINKL CAP has ranged from a low of $3.1462 (Sep 23, 2026) to a high of $5.5824 (Feb 11, 2026), with a median of $4.9252 per EA.
Are there cheaper alternatives to TOPIRAMATE ER 50 MG SPRINKL CAP?
5 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOPIRAMATE ER 50 MG SPRINKL CAP in a comparable dosage form, but none are currently priced below it.
Who manufactures TOPIRAMATE ER 50 MG SPRINKL CAP?
TOPIRAMATE ER 50 MG SPRINKL CAP (NDC 69680017830) is labeled by Vitruvias Therapeutics Inc., and CMS classifies it as a generic product.