Product Information
NICOTINE 21 MG/24HR PATCH is a generic product labeled by Cardinal Health, priced at $1.7558 per EA under NDC 70000051201. Its NADAC has been published 329 times since May 6, 2020.
FDA first approved this application on Oct 20, 1997.
Strength
21 mg/24h
Manufacturer
Cardinal HealthNDC
70000051201
Classification
Generic
Dosage Form
PATCH, EXTENDED RELEASE
Route
TRANSDERMAL
Effective Date
8/19/2026
Active Ingredients
NICOTINEApproval Type
Generic (ANDA)
FDA Application
ANDA074612FDA Approved
10/20/1997
On Market Since
9/1/2024
Pharmacological Classes
Price Statistics
The NADAC for NICOTINE 21 MG/24HR PATCH has been published 329 times since May 6, 2020, and over the history we have for it it has risen 3.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.7558 per EA |
|---|---|
| All-time high | $1.7719 (Jul 15, 2026) |
| All-time low | $1.2564 (Apr 17, 2024) |
| 52-week high | $1.7719 |
| 52-week low | $1.4808 |
| Median price | $1.5959 |
| Average price | $1.5981 |
| Largest weekly change | -20.6% (Apr 17, 2024) |
| Weeks tracked | 329 |
| Tracking since | May 6, 2020 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of NICOTINE 21 MG/24HR PATCH?
The current National Average Drug Acquisition Cost (NADAC) for NICOTINE 21 MG/24HR PATCH, manufactured by Cardinal Health, is $1.7558 per EA (NDC 70000051201), effective Aug 19, 2026.
How has the price of NICOTINE 21 MG/24HR PATCH changed over time?
Over the history we have for it, the NADAC for NICOTINE 21 MG/24HR PATCH has risen 3.6%. It has been tracked across 329 weekly CMS publications since May 6, 2020.
What are the highest and lowest recorded NADAC prices for NICOTINE 21 MG/24HR PATCH?
Since May 6, 2020, the NADAC for NICOTINE 21 MG/24HR PATCH has ranged from a low of $1.2564 (Apr 17, 2024) to a high of $1.7719 (Jul 15, 2026), with a median of $1.5959 per EA.
Are there cheaper alternatives to NICOTINE 21 MG/24HR PATCH?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as NICOTINE 21 MG/24HR PATCH in a comparable dosage form, but none are currently priced below it.
Who manufactures NICOTINE 21 MG/24HR PATCH?
NICOTINE 21 MG/24HR PATCH (NDC 70000051201) is labeled by Cardinal Health, and CMS classifies it as a generic product.