Product Information

TOPROL XL 25 MG TABLET is a brand product labeled by Melinta Therapeutics, LLC, priced at $1.3856 per EA under NDC 70842011002. Its NADAC has been published 154 times since Sep 13, 2023.

FDA first approved this application on Jan 10, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Metoprolol Succinate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

TOPROL XL 25 MG TABLET

Metoprolol Succinate
$1.3856per EA
High Outlier

Strength

25 mg/1

NDC

70842011002

Classification

Brand

Dosage Form

TABLET, EXTENDED RELEASE

Route

ORAL

Effective Date

7/1/2026

Active Ingredients

METOPROLOL SUCCINATE

Approval Type

New Drug (NDA)

FDA Application

NDA019962

FDA Approved

1/10/1992

TE Code

AB

On Market Since

7/3/2023

Pharmacological Classes

Adrenergic beta-Antagonists
beta-Adrenergic Blocker

Price Statistics

The NADAC for TOPROL XL 25 MG TABLET has been published 154 times since Sep 13, 2023, and over the history we have for it it has risen 10.5%. The table below summarizes its recorded NADAC range and movement.

Current price$1.3856 per EA
All-time high$1.3856 (Aug 19, 2026)
All-time low$1.2536 (Sep 13, 2023)
52-week high$1.3856
52-week low$1.3193
Median price$1.3185
Average price$1.2984
Largest weekly change+5.0% (Jul 1, 2026)
Weeks tracked154
Tracking sinceSep 13, 2023

Price History

1W

0.0%

1M

0.0%

3M

+5.0%

6M

+5.0%

1Y

+5.0%

3Y

N/A

5Y

N/A

All

+10.5%

Generic Alternatives

The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 96% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TOPROL XL 25 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for TOPROL XL 25 MG TABLET, manufactured by Melinta Therapeutics, LLC, is $1.3856 per EA (NDC 70842011002), effective Aug 19, 2026.

How has the price of TOPROL XL 25 MG TABLET changed over time?

Over the history we have for it, the NADAC for TOPROL XL 25 MG TABLET has risen 10.5%. It has been tracked across 154 weekly CMS publications since Sep 13, 2023.

What are the highest and lowest recorded NADAC prices for TOPROL XL 25 MG TABLET?

Since Sep 13, 2023, the NADAC for TOPROL XL 25 MG TABLET has ranged from a low of $1.2536 (Sep 13, 2023) to a high of $1.3856 (Aug 19, 2026), with a median of $1.3185 per EA.

Are there cheaper alternatives to TOPROL XL 25 MG TABLET?

Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METOPROLOL SUCC ER 25 MG TAB, is $0.0495 per EA — about 96% below TOPROL XL 25 MG TABLET.

Who manufactures TOPROL XL 25 MG TABLET?

TOPROL XL 25 MG TABLET (NDC 70842011002) is labeled by Melinta Therapeutics, LLC, and CMS classifies it as a brand product.