Product Information
TOPROL XL 25 MG TABLET is a brand product labeled by Melinta Therapeutics, LLC, priced at $1.3856 per EA under NDC 70842011002. Its NADAC has been published 160 times since Sep 13, 2023.
FDA first approved this application on Jan 10, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Metoprolol Succinate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
25 mg/1
Manufacturer
Melinta Therapeutics, LLCNDC
70842011002
Classification
Brand
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
7/1/2026
Active Ingredients
METOPROLOL SUCCINATEApproval Type
New Drug (NDA)
FDA Application
NDA019962FDA Approved
1/10/1992
TE Code
AB
On Market Since
7/3/2023
Pharmacological Classes
Price Statistics
The NADAC for TOPROL XL 25 MG TABLET has been published 160 times since Sep 13, 2023, and over the history we have for it it has risen 10.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3856 per EA |
|---|---|
| All-time high | $1.3856 (Sep 30, 2026) |
| All-time low | $1.2536 (Sep 13, 2023) |
| 52-week high | $1.3856 |
| 52-week low | $1.3193 |
| Median price | $1.3193 |
| Average price | $1.3016 |
| Largest weekly change | +5.0% (Jul 1, 2026) |
| Weeks tracked | 160 |
| Tracking since | Sep 13, 2023 |
Generic Alternatives
The matcher finds 5 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 97% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Melinta Therapeutics, LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Metoprolol Succinate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
beta-Adrenergic Blocker class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of TOPROL XL 25 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TOPROL XL 25 MG TABLET, manufactured by Melinta Therapeutics, LLC, is $1.3856 per EA (NDC 70842011002), effective Sep 30, 2026.
How has the price of TOPROL XL 25 MG TABLET changed over time?
Over the history we have for it, the NADAC for TOPROL XL 25 MG TABLET has risen 10.5%. It has been tracked across 160 weekly CMS publications since Sep 13, 2023.
What are the highest and lowest recorded NADAC prices for TOPROL XL 25 MG TABLET?
Since Sep 13, 2023, the NADAC for TOPROL XL 25 MG TABLET has ranged from a low of $1.2536 (Sep 13, 2023) to a high of $1.3856 (Sep 30, 2026), with a median of $1.3193 per EA.
Are there cheaper alternatives to TOPROL XL 25 MG TABLET?
Yes. 5 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METOPROLOL SUCC ER 25 MG TAB, is $0.0476 per EA — about 97% below TOPROL XL 25 MG TABLET.
Who manufactures TOPROL XL 25 MG TABLET?
TOPROL XL 25 MG TABLET (NDC 70842011002) is labeled by Melinta Therapeutics, LLC, and CMS classifies it as a brand product.