Product Information
TOPROL XL 50 MG TABLET is a brand product labeled by Melinta Therapeutics, LLC, priced at $1.3853 per EA under NDC 70842011102. Its NADAC has been published 154 times since Sep 13, 2023.
FDA first approved this application on Jan 10, 1992. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Metoprolol Succinate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
50 mg/1
Manufacturer
Melinta Therapeutics, LLCNDC
70842011102
Classification
Brand
Dosage Form
TABLET, EXTENDED RELEASE
Route
ORAL
Effective Date
7/1/2026
Active Ingredients
METOPROLOL SUCCINATEApproval Type
New Drug (NDA)
FDA Application
NDA019962FDA Approved
1/10/1992
TE Code
AB
On Market Since
7/3/2023
Pharmacological Classes
Price Statistics
The NADAC for TOPROL XL 50 MG TABLET has been published 154 times since Sep 13, 2023, and over the history we have for it it has risen 9.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3853 per EA |
|---|---|
| All-time high | $1.3853 (Aug 19, 2026) |
| All-time low | $1.2527 (Nov 22, 2023) |
| 52-week high | $1.3853 |
| 52-week low | $1.3191 |
| Median price | $1.3193 |
| Average price | $1.2968 |
| Largest weekly change | +5.0% (Jan 1, 2025) |
| Weeks tracked | 154 |
| Tracking since | Sep 13, 2023 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 96% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of TOPROL XL 50 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for TOPROL XL 50 MG TABLET, manufactured by Melinta Therapeutics, LLC, is $1.3853 per EA (NDC 70842011102), effective Aug 19, 2026.
How has the price of TOPROL XL 50 MG TABLET changed over time?
Over the history we have for it, the NADAC for TOPROL XL 50 MG TABLET has risen 9.8%. It has been tracked across 154 weekly CMS publications since Sep 13, 2023.
What are the highest and lowest recorded NADAC prices for TOPROL XL 50 MG TABLET?
Since Sep 13, 2023, the NADAC for TOPROL XL 50 MG TABLET has ranged from a low of $1.2527 (Nov 22, 2023) to a high of $1.3853 (Aug 19, 2026), with a median of $1.3193 per EA.
Are there cheaper alternatives to TOPROL XL 50 MG TABLET?
Yes. 4 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METOPROLOL SUCC ER 50 MG TAB, is $0.0570 per EA — about 96% below TOPROL XL 50 MG TABLET.
Who manufactures TOPROL XL 50 MG TABLET?
TOPROL XL 50 MG TABLET (NDC 70842011102) is labeled by Melinta Therapeutics, LLC, and CMS classifies it as a brand product.