Product Information

GVOKE HYPOPEN 2-PK 1 MG/0.2 ML is a brand product labeled by Xeris Pharmaceuticals, Inc., priced at $1596.1935 per ML under NDC 72065012112. Its NADAC has been published 311 times since Oct 21, 2020.

FDA first approved this application on Sep 10, 2019.

GVOKE HYPOPEN 2-PK 1 MG/0.2 ML

glucagon injection, solution
$1596.1935per ML

Strength

1 mg/.2mL

NDC

72065012112

Classification

Brand

Dosage Form

INJECTION, SOLUTION

Route

SUBCUTANEOUS

Effective Date

9/23/2026

Active Ingredients

GLUCAGON

Approval Type

New Drug (NDA)

FDA Application

NDA212097

FDA Approved

9/10/2019

On Market Since

9/10/2019

Pharmacological Classes

Antihypoglycemic Agent
Decreased GI Motility
Decreased GI Smooth Muscle Tone
Decreased Glycolysis
Gastrointestinal Motility Inhibitor
Increased Gluconeogenesis
Increased Glycogenolysis

Price Statistics

The NADAC for GVOKE HYPOPEN 2-PK 1 MG/0.2 ML has been published 311 times since Oct 21, 2020, and over the history we have for it it has risen 18.2%. The table below summarizes its recorded NADAC range and movement.

Current price$1596.1935 per ML
All-time high$1603.3466 (Sep 16, 2026)
All-time low$1341.3857 (May 19, 2021)
52-week high$1603.3466
52-week low$1552.9905
Median price$1465.7826
Average price$1473.2472
Largest weekly change+3.0% (Feb 15, 2023)
Weeks tracked311
Tracking sinceOct 21, 2020

Price History

1W

0.0%

1M

-0.4%

3M

-0.1%

6M

-0.2%

1Y

+2.8%

3Y

+8.9%

5Y

+15.5%

All

+18.2%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Continue researching this drug

Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.

Frequently asked questions

What is the NADAC price of GVOKE HYPOPEN 2-PK 1 MG/0.2 ML?

The current National Average Drug Acquisition Cost (NADAC) for GVOKE HYPOPEN 2-PK 1 MG/0.2 ML, manufactured by Xeris Pharmaceuticals, Inc., is $1596.1935 per ML (NDC 72065012112), effective Sep 30, 2026.

How has the price of GVOKE HYPOPEN 2-PK 1 MG/0.2 ML changed over time?

Over the history we have for it, the NADAC for GVOKE HYPOPEN 2-PK 1 MG/0.2 ML has risen 18.2%. It has been tracked across 311 weekly CMS publications since Oct 21, 2020.

What are the highest and lowest recorded NADAC prices for GVOKE HYPOPEN 2-PK 1 MG/0.2 ML?

Since Oct 21, 2020, the NADAC for GVOKE HYPOPEN 2-PK 1 MG/0.2 ML has ranged from a low of $1341.3857 (May 19, 2021) to a high of $1603.3466 (Sep 16, 2026), with a median of $1465.7826 per ML.

Are there cheaper alternatives to GVOKE HYPOPEN 2-PK 1 MG/0.2 ML?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as GVOKE HYPOPEN 2-PK 1 MG/0.2 ML in a comparable dosage form, but none are currently priced below it.

Who manufactures GVOKE HYPOPEN 2-PK 1 MG/0.2 ML?

GVOKE HYPOPEN 2-PK 1 MG/0.2 ML (NDC 72065012112) is labeled by Xeris Pharmaceuticals, Inc., and CMS classifies it as a brand product.