Product Information

CIPROFLOXACIN 0.3% EYE DROP is a generic product labeled by Advagen Pharma Ltd., priced at $0.7990 per ML under NDC 72888010223. Its NADAC has been published 54 times since Aug 13, 2025.

FDA first approved this application on Jun 9, 2004. Its Orange Book therapeutic-equivalence code is AT.

CIPROFLOXACIN 0.3% EYE DROP

CIPROFLOXACIN HYDROCHLORIDE
$0.7990per ML

Strength

3 mg/mL

NDC

72888010223

Classification

Generic

Dosage Form

SOLUTION

Route

OPHTHALMIC

Effective Date

8/19/2026

Active Ingredients

CIPROFLOXACIN HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA075928

FDA Approved

6/9/2004

TE Code

AT

On Market Since

3/16/2022

Pharmacological Classes

Cytochrome P450 1A2 Inhibitors
Fluoroquinolone Antibacterial
Fluoroquinolones

Price Statistics

The NADAC for CIPROFLOXACIN 0.3% EYE DROP has been published 54 times since Aug 13, 2025, and over the history we have for it it has declined 29.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.7990 per ML
All-time high$1.2740 (Oct 15, 2025)
All-time low$0.7990 (Aug 19, 2026)
52-week high$1.2740
52-week low$0.7990
Median price$0.9436
Average price$1.0047
Largest weekly change-13.7% (Nov 19, 2025)
Weeks tracked54
Tracking sinceAug 13, 2025

Price History

1W

-5.8%

1M

-5.8%

3M

-10.7%

6M

-14.1%

1Y

-34.5%

3Y

N/A

5Y

N/A

All

-29.1%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CIPROFLOXACIN 0.3% EYE DROP?

The current National Average Drug Acquisition Cost (NADAC) for CIPROFLOXACIN 0.3% EYE DROP, manufactured by Advagen Pharma Ltd., is $0.7990 per ML (NDC 72888010223), effective Aug 19, 2026.

How has the price of CIPROFLOXACIN 0.3% EYE DROP changed over time?

Over the history we have for it, the NADAC for CIPROFLOXACIN 0.3% EYE DROP has declined 29.1%. It has been tracked across 54 weekly CMS publications since Aug 13, 2025.

What are the highest and lowest recorded NADAC prices for CIPROFLOXACIN 0.3% EYE DROP?

Since Aug 13, 2025, the NADAC for CIPROFLOXACIN 0.3% EYE DROP has ranged from a low of $0.7990 (Aug 19, 2026) to a high of $1.2740 (Oct 15, 2025), with a median of $0.9436 per ML.

Are there cheaper alternatives to CIPROFLOXACIN 0.3% EYE DROP?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as CIPROFLOXACIN 0.3% EYE DROP in a comparable dosage form, but none are currently priced below it.

Who manufactures CIPROFLOXACIN 0.3% EYE DROP?

CIPROFLOXACIN 0.3% EYE DROP (NDC 72888010223) is labeled by Advagen Pharma Ltd., and CMS classifies it as a generic product.