Product Information

TOPIRAMATE 100 MG TABLET is a generic product labeled by Exelan Pharmaceuticals Inc., priced at $0.0550 per EA under NDC 76282028010. Its NADAC has been published 298 times since Dec 9, 2020.

FDA first approved this application on Mar 27, 2009. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

TOPIRAMATE 100 MG TABLET

Topiramate
$0.0550per EA

Strength

100 mg/1

NDC

76282028010

Classification

Generic

Dosage Form

TABLET

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

TOPIRAMATE

Approval Type

Generic (ANDA)

FDA Application

ANDA079162

FDA Approved

3/27/2009

TE Code

AB

On Market Since

9/7/2020

Pharmacological Classes

Cytochrome P450 2C19 Inhibitors
Cytochrome P450 3A4 Inducers
Decreased Central Nervous System Disorganized Electrical Activity

Price Statistics

The NADAC for TOPIRAMATE 100 MG TABLET has been published 298 times since Dec 9, 2020, and over the history we have for it it has declined 22.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0550 per EA
All-time high$0.0711 (Dec 16, 2020)
All-time low$0.0486 (Nov 20, 2024)
52-week high$0.0645
52-week low$0.0550
Median price$0.0643
Average price$0.0638
Largest weekly change+33.1% (Aug 21, 2024)
Weeks tracked298
Tracking sinceDec 9, 2020

Price History

1W

-1.0%

1M

-1.0%

3M

-7.5%

6M

-6.7%

1Y

-14.7%

3Y

-13.3%

5Y

-19.5%

All

-22.6%

Generic Alternatives

The matcher finds 6 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of TOPIRAMATE 100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for TOPIRAMATE 100 MG TABLET, manufactured by Exelan Pharmaceuticals Inc., is $0.0550 per EA (NDC 76282028010), effective Aug 19, 2026.

How has the price of TOPIRAMATE 100 MG TABLET changed over time?

Over the history we have for it, the NADAC for TOPIRAMATE 100 MG TABLET has declined 22.6%. It has been tracked across 298 weekly CMS publications since Dec 9, 2020.

What are the highest and lowest recorded NADAC prices for TOPIRAMATE 100 MG TABLET?

Since Dec 9, 2020, the NADAC for TOPIRAMATE 100 MG TABLET has ranged from a low of $0.0486 (Nov 20, 2024) to a high of $0.0711 (Dec 16, 2020), with a median of $0.0643 per EA.

Are there cheaper alternatives to TOPIRAMATE 100 MG TABLET?

6 manufacturers publish a NADAC-priced product with the same active ingredient and strength as TOPIRAMATE 100 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures TOPIRAMATE 100 MG TABLET?

TOPIRAMATE 100 MG TABLET (NDC 76282028010) is labeled by Exelan Pharmaceuticals Inc., and CMS classifies it as a generic product.