Product Information

AUVELITY ER 45-105 MG TABLET is a brand product labeled by Axsome Therapeutics, Inc., priced at $19.8954 per EA under NDC 81968004560. Its NADAC has been published 75 times since Jan 22, 2025.

AUVELITY ER 45-105 MG TABLET

dextromethorphan hydrobromide, bupropion hydrochloride
$19.8954per EA

Strength

105; 45 mg/1; mg/1

NDC

81968004560

Classification

Brand

Dosage Form

TABLET, MULTILAYER, EXTENDED RELEASE

Route

ORAL

Last Updated

6/17/2026

Approval Type

New Drug (NDA)

FDA Application

NDA215430

On Market Since

8/18/2022

Pharmacological Classes

Aminoketone
Dopamine Uptake Inhibitors
Increased Dopamine Activity
Increased Norepinephrine Activity
Norepinephrine Uptake Inhibitors
Sigma-1 Agonist
Sigma-1 Receptor Agonists
Uncompetitive N-methyl-D-aspartate Receptor Antagonist
Uncompetitive NMDA Receptor Antagonists

Price Statistics

The NADAC for AUVELITY ER 45-105 MG TABLET has been published 75 times since Jan 22, 2025, and over the history we have for it it has risen 5.8%. The table below summarizes its recorded NADAC range and movement.

Current price$19.8954 per EA
All-time high$19.8957 (Jun 10, 2026)
All-time low$18.7521 (Aug 20, 2025)
52-week high$19.8957
52-week low$18.7521
Median price$18.8044
Average price$19.1580
Largest weekly change+6.0% (Dec 31, 2025)
Weeks tracked75
Tracking sinceJan 22, 2025

Price History

1W

0.0%

1M

-0.0%

3M

+0.1%

6M

+6.1%

1Y

+6.1%

3Y

N/A

5Y

N/A

All

+5.8%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of AUVELITY ER 45-105 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for AUVELITY ER 45-105 MG TABLET, manufactured by Axsome Therapeutics, Inc., is $19.8954 per EA (NDC 81968004560), effective Jun 24, 2026.

How has the price of AUVELITY ER 45-105 MG TABLET changed over time?

Over the history we have for it, the NADAC for AUVELITY ER 45-105 MG TABLET has risen 5.8%. It has been tracked across 75 weekly CMS publications since Jan 22, 2025.

What are the highest and lowest recorded NADAC prices for AUVELITY ER 45-105 MG TABLET?

Since Jan 22, 2025, the NADAC for AUVELITY ER 45-105 MG TABLET has ranged from a low of $18.7521 (Aug 20, 2025) to a high of $19.8957 (Jun 10, 2026), with a median of $18.8044 per EA.

Are there cheaper alternatives to AUVELITY ER 45-105 MG TABLET?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as AUVELITY ER 45-105 MG TABLET, but none are currently priced below it.

Who manufactures AUVELITY ER 45-105 MG TABLET?

AUVELITY ER 45-105 MG TABLET (NDC 81968004560) is labeled by Axsome Therapeutics, Inc., and CMS classifies it as a brand product.