Product Information
AUVELITY ER 45-105 MG TABLET is a brand product labeled by Axsome Therapeutics, Inc., priced at $19.8959 per EA under NDC 81968004560. Its NADAC has been published 83 times since Jan 22, 2025.
FDA first approved this application on Aug 18, 2022.
Strength
105; 45 mg/1; mg/1
Manufacturer
Axsome Therapeutics, Inc.NDC
81968004560
Classification
Brand
Dosage Form
TABLET, MULTILAYER, EXTENDED RELEASE
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
BUPROPION HYDROCHLORIDE; DEXTROMETHORPHAN HYDROBROMIDEApproval Type
New Drug (NDA)
FDA Application
NDA215430FDA Approved
8/18/2022
On Market Since
8/18/2022
Pharmacological Classes
Price Statistics
The NADAC for AUVELITY ER 45-105 MG TABLET has been published 83 times since Jan 22, 2025, and over the history we have for it it has risen 5.8%. The table below summarizes its recorded NADAC range and movement.
| Current price | $19.8959 per EA |
|---|---|
| All-time high | $19.8959 (Aug 19, 2026) |
| All-time low | $18.7521 (Aug 20, 2025) |
| 52-week high | $19.8959 |
| 52-week low | $18.7521 |
| Median price | $18.8044 |
| Average price | $19.2288 |
| Largest weekly change | +6.0% (Dec 31, 2025) |
| Weeks tracked | 83 |
| Tracking since | Jan 22, 2025 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of AUVELITY ER 45-105 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for AUVELITY ER 45-105 MG TABLET, manufactured by Axsome Therapeutics, Inc., is $19.8959 per EA (NDC 81968004560), effective Aug 19, 2026.
How has the price of AUVELITY ER 45-105 MG TABLET changed over time?
Over the history we have for it, the NADAC for AUVELITY ER 45-105 MG TABLET has risen 5.8%. It has been tracked across 83 weekly CMS publications since Jan 22, 2025.
What are the highest and lowest recorded NADAC prices for AUVELITY ER 45-105 MG TABLET?
Since Jan 22, 2025, the NADAC for AUVELITY ER 45-105 MG TABLET has ranged from a low of $18.7521 (Aug 20, 2025) to a high of $19.8959 (Aug 19, 2026), with a median of $18.8044 per EA.
Are there cheaper alternatives to AUVELITY ER 45-105 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as AUVELITY ER 45-105 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures AUVELITY ER 45-105 MG TABLET?
AUVELITY ER 45-105 MG TABLET (NDC 81968004560) is labeled by Axsome Therapeutics, Inc., and CMS classifies it as a brand product.