Product Information
BRIMONIDINE TARTRATE 0.1% DROP is a generic product labeled by Pacific Pharma, Inc., priced at $6.5539 per ML under NDC 82182032115. Its NADAC has been published 129 times since Apr 17, 2024.
FDA first approved this application on Aug 19, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
1 mg/mL
Manufacturer
Pacific Pharma, Inc.NDC
82182032115
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
BRIMONIDINE TARTRATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021770FDA Approved
8/19/2005
TE Code
AB
On Market Since
1/2/2024
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE TARTRATE 0.1% DROP has been published 129 times since Apr 17, 2024, and over the history we have for it it has declined 74.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6.5539 per ML |
|---|---|
| All-time high | $25.4636 (May 15, 2024) |
| All-time low | $6.5539 (Sep 23, 2026) |
| 52-week high | $14.2435 |
| 52-week low | $6.5539 |
| Median price | $14.1665 |
| Average price | $14.6065 |
| Largest weekly change | -15.4% (Jul 22, 2026) |
| Weeks tracked | 129 |
| Tracking since | Apr 17, 2024 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Pacific Pharma, Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
brimonidine tartrate market comparison
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Therapeutic class
alpha-Adrenergic Agonist class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of BRIMONIDINE TARTRATE 0.1% DROP?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE TARTRATE 0.1% DROP, manufactured by Pacific Pharma, Inc., is $6.5539 per ML (NDC 82182032115), effective Sep 30, 2026.
How has the price of BRIMONIDINE TARTRATE 0.1% DROP changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE TARTRATE 0.1% DROP has declined 74.3%. It has been tracked across 129 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE TARTRATE 0.1% DROP?
Since Apr 17, 2024, the NADAC for BRIMONIDINE TARTRATE 0.1% DROP has ranged from a low of $6.5539 (Sep 23, 2026) to a high of $25.4636 (May 15, 2024), with a median of $14.1665 per ML.
Are there cheaper alternatives to BRIMONIDINE TARTRATE 0.1% DROP?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as BRIMONIDINE TARTRATE 0.1% DROP in a comparable dosage form, but none are currently priced below it.
Who manufactures BRIMONIDINE TARTRATE 0.1% DROP?
BRIMONIDINE TARTRATE 0.1% DROP (NDC 82182032115) is labeled by Pacific Pharma, Inc., and CMS classifies it as a generic product.