Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Pacific Pharma, Inc., priced at $2.8820 per ML under NDC 82182045505. Its NADAC has been published 189 times since Nov 16, 2022.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Pacific Pharma, Inc.NDC
82182045505
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021398On Market Since
10/21/2022
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 189 times since Nov 16, 2022, and over the history we have for it it has declined 90.1%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.8820 per ML |
|---|---|
| All-time high | $30.1545 (Dec 14, 2022) |
| All-time low | $2.8820 (Jun 17, 2026) |
| 52-week high | $5.4857 |
| 52-week low | $2.8820 |
| Median price | $8.1686 |
| Average price | $10.7932 |
| Largest weekly change | -37.2% (Jul 17, 2024) |
| Weeks tracked | 189 |
| Tracking since | Nov 16, 2022 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 27% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Pacific Pharma, Inc., is $2.8820 per ML (NDC 82182045505), effective Jun 24, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 90.1%. It has been tracked across 189 weekly CMS publications since Nov 16, 2022.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Nov 16, 2022, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.8820 (Jun 17, 2026) to a high of $30.1545 (Dec 14, 2022), with a median of $8.1686 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, BRIMONIDINE-TIMOLOL 0.2%-0.5%, is $2.1018 per ML — about 27% below BRIMONIDINE-TIMOLOL 0.2%-0.5%.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 82182045505) is labeled by Pacific Pharma, Inc., and CMS classifies it as a generic product.
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