Product Information
BRIMONIDINE-TIMOLOL 0.2%-0.5% is a generic product labeled by Pacific Pharma, Inc., priced at $2.1018 per ML under NDC 82182045515. Its NADAC has been published 189 times since Nov 16, 2022.
Strength
2; 5 mg/mL; mg/mL
Manufacturer
Pacific Pharma, Inc.NDC
82182045515
Classification
Generic
Dosage Form
SOLUTION/ DROPS
Route
TOPICAL
Last Updated
6/17/2026
Active Ingredients
BRIMONIDINE TARTRATE; TIMOLOL MALEATEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021398On Market Since
10/21/2022
Pharmacological Classes
Price Statistics
The NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has been published 189 times since Nov 16, 2022, and over the history we have for it it has declined 92.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $2.1018 per ML |
|---|---|
| All-time high | $30.7775 (Dec 14, 2022) |
| All-time low | $2.1018 (Jun 17, 2026) |
| 52-week high | $6.8975 |
| 52-week low | $2.1018 |
| Median price | $9.0342 |
| Average price | $10.7267 |
| Largest weekly change | +75.9% (Aug 21, 2024) |
| Weeks tracked | 189 |
| Tracking since | Nov 16, 2022 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of BRIMONIDINE-TIMOLOL 0.2%-0.5%?
The current National Average Drug Acquisition Cost (NADAC) for BRIMONIDINE-TIMOLOL 0.2%-0.5%, manufactured by Pacific Pharma, Inc., is $2.1018 per ML (NDC 82182045515), effective Jun 24, 2026.
How has the price of BRIMONIDINE-TIMOLOL 0.2%-0.5% changed over time?
Over the history we have for it, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has declined 92.9%. It has been tracked across 189 weekly CMS publications since Nov 16, 2022.
What are the highest and lowest recorded NADAC prices for BRIMONIDINE-TIMOLOL 0.2%-0.5%?
Since Nov 16, 2022, the NADAC for BRIMONIDINE-TIMOLOL 0.2%-0.5% has ranged from a low of $2.1018 (Jun 17, 2026) to a high of $30.7775 (Dec 14, 2022), with a median of $9.0342 per ML.
Are there cheaper alternatives to BRIMONIDINE-TIMOLOL 0.2%-0.5%?
1 NADAC-published product shares the same active ingredient, strength, and dosage form as BRIMONIDINE-TIMOLOL 0.2%-0.5%, but none are currently priced below it.
Who manufactures BRIMONIDINE-TIMOLOL 0.2%-0.5%?
BRIMONIDINE-TIMOLOL 0.2%-0.5% (NDC 82182045515) is labeled by Pacific Pharma, Inc., and CMS classifies it as a generic product.
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