Aprepitant
27 NDCs across 5 manufacturers|24 Generic,3 Brand
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The brand product was first FDA-approved on Mar 26, 2003, and the first generic was approved Sep 24, 2012. FDA's Orange Book lists 11 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $8 million on Aprepitant across 13,000 claims for 5,647 beneficiaries.
Aprepitant is available as 27 NDCs from 5 manufacturers (24 generic, 3 brand), with NADAC prices from $46.42 to $327.38 per EA — the most expensive product costs about 7.1× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
27
24G / 3B
Manufacturers
5
competing in market
Price Spread
$46.42 – $327.38
per EA
7d Activity
avg -0.1% WoW · of 27 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Torrent Pharmaceuticals Limited manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Substance P/Neurokinin-1 Receptor Antagonist class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
5 manufacturers producing APREPITANT(1 pricing outlier)
Frequently Asked Questions
When did Aprepitant become available as a generic?
FDA approved the first generic Aprepitant (ANDA) on Sep 24, 2012. The Orange Book currently lists 11 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Aprepitant?
In 2024, Medicare Part D spent $8 million on Aprepitant across 13,000 claims for 5,647 beneficiaries.
How many Aprepitant products are on the market?
The Aprepitant drug market contains 27 NDCs from 5 manufacturers — 24 generic and 3 brand products.
What is the price range for Aprepitant?
NADAC reference prices for Aprepitant range from $46.4206 to $327.3840 per EA — the most expensive product costs about 7.1× the cheapest.
Is generic Aprepitant cheaper than brand?
The average generic NADAC for Aprepitant is $74.1012 per EA, versus $260.7953 for brand-labeled products — brand versions average about 3.5× the generic price.
Which manufacturers make Aprepitant?
5 manufacturers list Aprepitant in NADAC. Ranked by number of NDCs, the largest are Torrent Pharmaceuticals Limited (6), Sandoz Inc. (6), BluePoint Laboratories (6), Glenmark Pharmaceuticals Inc., USA (6), Merck Sharp & Dohme LLC (3).
How has the price of Aprepitant changed recently?
Over the past 7 days, 8 Aprepitant NDCs rose and 16 fell, with a market-wide average change of -0.1%.