Fentanyl
22 NDCs across 4 manufacturers|22 Generic,0 Brand
Fentanyl is used to treat pain, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on Aug 7, 1990, and the first generic was approved Jan 28, 2005. FDA's Orange Book lists 28 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $92 million on Fentanyl across 821,000 claims for 117,000 beneficiaries.
Fentanyl is available as 22 NDCs from 4 manufacturers (22 generic, 0 brand), with NADAC prices from $6.01 to $35.03 per EA — the most expensive product costs about 5.8× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Active FDA drug shortage
19 Fentanyl presentations are currently listed in FDA's drug shortage database (first posted Jan 1, 2012). Shortages can move NADAC prices in the following weeks.
Total NDCs
22
22G / 0B
Manufacturers
4
competing in market
Price Spread
$6.01 – $35.03
per EA
7d Activity
avg +1.0% WoW · of 22 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
Mylan Pharmaceuticals Inc. manufacturer profile
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Lead class
Opioid Agonist class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
4 manufacturers producing FENTANYL
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
FENTANYL 37.5 MCG/HR PATCH | $35.0269 per EA | +1.70% |
FENTANYL 37.5 MCG/HR PATCH | $35.0269 per EA | +1.70% |
FENTANYL 100 MCG/HR PATCH | $18.3579 per EA | +1.22% |
FENTANYL 100 MCG/HR PATCH | $18.3579 per EA | +1.22% |
FENTANYL 100 MCG/HR PATCH | $18.3579 per EA | +1.22% |
FENTANYL 75 MCG/HR PATCH | $15.8712 per EA | +2.77% |
FENTANYL 75 MCG/HR PATCH | $15.8712 per EA | +2.77% |
FENTANYL 75 MCG/HR PATCH | $15.8712 per EA | +2.77% |
FENTANYL 12 MCG/HR PATCH | $9.8055 per EA | — |
FENTANYL 12 MCG/HR PATCH | $9.8055 per EA | — |
FENTANYL 50 MCG/HR PATCH | $9.7741 per EA | — |
FENTANYL 50 MCG/HR PATCH | $9.7675 per EA | — |
FENTANYL 50 MCG/HR PATCH | $9.0700 per EA | -1.57% |
FENTANYL 50 MCG/HR PATCH | $9.0700 per EA | -1.57% |
FENTANYL 50 MCG/HR PATCH | $9.0700 per EA | -1.57% |
FENTANYL 12 MCG/HR PATCH | $8.9890 per EA | -1.13% |
FENTANYL 12 MCG/HR PATCH | $8.9890 per EA | -1.13% |
FENTANYL 12 MCG/HR PATCH | $8.9890 per EA | -1.13% |
FENTANYL 50 MCG/HR PATCH | $8.4477 per EA | — |
FENTANYL 25 MCG/HR PATCH | $6.0145 per EA | +3.24% |
FENTANYL 25 MCG/HR PATCH | $6.0145 per EA | +3.24% |
FENTANYL 25 MCG/HR PATCH | $6.0145 per EA | +3.24% |
Frequently Asked Questions
What is Fentanyl used to treat?
Fentanyl is used to treat pain, per the National Library of Medicine's MED-RT classification.
When did Fentanyl become available as a generic?
FDA approved the first generic Fentanyl (ANDA) on Jan 28, 2005. The Orange Book currently lists 28 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Fentanyl?
In 2024, Medicare Part D spent $92 million on Fentanyl across 821,000 claims for 117,000 beneficiaries.
Is Fentanyl in shortage?
Yes — FDA's drug shortage database currently lists 19 Fentanyl presentations with status "Current", first posted Jan 1, 2012.
How many Fentanyl products are on the market?
The Fentanyl drug market contains 22 NDCs from 4 manufacturers — 22 generic and 0 brand products.
What is the price range for Fentanyl?
NADAC reference prices for Fentanyl range from $6.0145 to $35.0269 per EA — the most expensive product costs about 5.8× the cheapest.
Which manufacturers make Fentanyl?
4 manufacturers list Fentanyl in NADAC. Ranked by number of NDCs, the largest are Mylan Pharmaceuticals Inc. (6), Ingenus Pharmaceuticals LLC (6), Alvogen Inc. (5), Apotex Corp. (5).
How has the price of Fentanyl changed recently?
Over the past 7 days, 11 Fentanyl NDCs rose and 6 fell, with a market-wide average change of +1.0%.