Product Information

FENTANYL 25 MCG/HR PATCH is a generic product labeled by Mylan Pharmaceuticals Inc., priced at $5.8258 per EA under NDC 00378912198. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Jan 28, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

FENTANYL 25 MCG/HR PATCH

FENTANYL
$5.8258per EA
DEA Schedule CII

Strength

25 ug/h

NDC

00378912198

Classification

Generic

Dosage Form

PATCH

Route

TRANSDERMAL

Effective Date

8/19/2026

Active Ingredients

FENTANYL

Approval Type

Generic (ANDA)

FDA Application

ANDA076258

FDA Approved

1/28/2005

TE Code

AB

On Market Since

1/31/2005

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for FENTANYL 25 MCG/HR PATCH has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 37.9%. The table below summarizes its recorded NADAC range and movement.

Current price$5.8258 per EA
All-time high$5.8258 (Aug 19, 2026)
All-time low$2.6808 (Apr 17, 2019)
52-week high$5.8258
52-week low$5.5481
Median price$3.7838
Average price$4.0623
Largest weekly change+24.3% (Jan 18, 2023)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+1.8%

1M

+1.9%

3M

+1.3%

6M

+2.0%

1Y

+4.4%

3Y

+11.8%

5Y

+54.5%

All

+37.9%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of FENTANYL 25 MCG/HR PATCH?

The current National Average Drug Acquisition Cost (NADAC) for FENTANYL 25 MCG/HR PATCH, manufactured by Mylan Pharmaceuticals Inc., is $5.8258 per EA (NDC 00378912198), effective Aug 19, 2026.

How has the price of FENTANYL 25 MCG/HR PATCH changed over time?

Over the history we have for it, the NADAC for FENTANYL 25 MCG/HR PATCH has risen 37.9%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for FENTANYL 25 MCG/HR PATCH?

Since Nov 28, 2013, the NADAC for FENTANYL 25 MCG/HR PATCH has ranged from a low of $2.6808 (Apr 17, 2019) to a high of $5.8258 (Aug 19, 2026), with a median of $3.7838 per EA.

Are there cheaper alternatives to FENTANYL 25 MCG/HR PATCH?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as FENTANYL 25 MCG/HR PATCH in a comparable dosage form, but none are currently priced below it.

Who manufactures FENTANYL 25 MCG/HR PATCH?

FENTANYL 25 MCG/HR PATCH (NDC 00378912198) is labeled by Mylan Pharmaceuticals Inc., and CMS classifies it as a generic product.