Midazolam
11 NDCs across 4 manufacturers|10 Generic,1 Brand
Midazolam is used to treat anxiety disorders, psychomotor agitation and status epilepticus, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved on May 17, 2019, and the first generic was approved Apr 17, 2023. In 2024, Medicare Part D spent $37 million on Midazolam across 39,000 claims for 18,000 beneficiaries.
Midazolam is available as 11 NDCs from 4 manufacturers (10 generic, 1 brand), with NADAC prices from $0.23 to $0.51 per ML — the most expensive product costs about 2.2× the cheapest. Every pack size and labeler in this drug market is compared side-by-side below.
Active FDA drug shortage
27 Midazolam presentations are currently listed in FDA's drug shortage database (first posted Apr 2, 2020). Shortages can move NADAC prices in the following weeks.
Total NDCs
11
10G / 1B
Manufacturers
4
competing in market
Price Spread
$0.23 – $0.51
per ML, 10 of 11 NDCs
7d Activity
avg -0.3% WoW · of 11 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Hikma Pharmaceuticals USA Inc. manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Benzodiazepine class view
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Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
4 manufacturers producing MIDAZOLAM
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
NAYZILAM 5 MG NASAL SPRAY | $327.0477 per EA | -0.09% |
MIDAZOLAM HCL 10 MG/2 ML VIAL | $0.5053 per ML | — |
MIDAZOLAM HCL 50 MG/10 ML VIAL | $0.4500 per ML | — |
MIDAZOLAM HCL 50 MG/10 ML VIAL | $0.3817 per ML | — |
MIDAZOLAM HCL 50 MG/10 ML VIAL | $0.3817 per ML | — |
MIDAZOLAM HCL 50 MG/10 ML VIAL | $0.3817 per ML | — |
MIDAZOLAM HCL 2 MG/2 ML VIAL | $0.2400 per ML | — |
MIDAZOLAM HCL 2 MG/2 ML VIAL | $0.2334 per ML | -0.38% |
MIDAZOLAM HCL 2 MG/2 ML VIAL | $0.2334 per ML | -0.38% |
MIDAZOLAM HCL 2 MG/2 ML VIAL | $0.2334 per ML | -0.38% |
MIDAZOLAM HCL 2 MG/2 ML VIAL | $0.2334 per ML | -0.38% |
Frequently Asked Questions
What is Midazolam used to treat?
Midazolam is used to treat anxiety disorders, psychomotor agitation and status epilepticus, per the National Library of Medicine's MED-RT classification.
When did Midazolam become available as a generic?
FDA approved the first generic Midazolam (ANDA) on Apr 17, 2023.
How much does Medicare spend on Midazolam?
In 2024, Medicare Part D spent $37 million on Midazolam across 39,000 claims for 18,000 beneficiaries.
Is Midazolam in shortage?
Yes — FDA's drug shortage database currently lists 27 Midazolam presentations with status "Current", first posted Apr 2, 2020.
How many Midazolam products are on the market?
The Midazolam drug market contains 11 NDCs from 4 manufacturers — 10 generic and 1 brand product.
What is the price range for Midazolam?
NADAC reference prices for Midazolam range from $0.2334 to $0.5053 per ML — the most expensive product costs about 2.2× the cheapest. 1 additional product is priced per a different unit (e.g. liquids per ML) and isn't directly comparable.
Which manufacturers make Midazolam?
4 manufacturers list Midazolam in NADAC. Ranked by number of NDCs, the largest are Hikma Pharmaceuticals USA Inc. (7), Almaject, Inc. (2), UCB, Inc. (1), Civica, Inc. (1).
How has the price of Midazolam changed recently?
Over the past 7 days, 0 Midazolam NDCs rose and 5 fell, with a market-wide average change of -0.3%.