Product Information

NAYZILAM 5 MG NASAL SPRAY is a brand product labeled by UCB, Inc., priced at $327.3481 per EA under NDC 50474050015. Its NADAC has been published 336 times since Mar 18, 2020.

FDA first approved this application on May 17, 2019.

The High Outlier badge above means this manufacturer's average price in the midazolam market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

NAYZILAM 5 MG NASAL SPRAY

midazolam
$327.3481per EA
High Outlier
DEA Schedule CIV

Strength

5 mg/.1mL

Manufacturer

UCB, Inc.

NDC

50474050015

Classification

Brand

Dosage Form

SPRAY

Route

NASAL

Effective Date

8/19/2026

Active Ingredients

MIDAZOLAM

Approval Type

New Drug (NDA)

FDA Application

NDA211321

FDA Approved

5/17/2019

On Market Since

5/17/2019

Pharmacological Classes

Benzodiazepine
Benzodiazepines

Price Statistics

The NADAC for NAYZILAM 5 MG NASAL SPRAY has been published 336 times since Mar 18, 2020, and over the history we have for it it has risen 24.0%. The table below summarizes its recorded NADAC range and movement.

Current price$327.3481 per EA
All-time high$327.6376 (May 13, 2026)
All-time low$263.8393 (Jan 20, 2021)
52-week high$327.6376
52-week low$319.2122
Median price$299.4883
Average price$294.5688
Largest weekly change+6.9% (Jan 12, 2022)
Weeks tracked336
Tracking sinceMar 18, 2020

Price History

1W

+0.1%

1M

+0.1%

3M

+0.1%

6M

-0.1%

1Y

+2.5%

3Y

+9.3%

5Y

+24.1%

All

+24.0%

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the midazolam market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of NAYZILAM 5 MG NASAL SPRAY?

The current National Average Drug Acquisition Cost (NADAC) for NAYZILAM 5 MG NASAL SPRAY, manufactured by UCB, Inc., is $327.3481 per EA (NDC 50474050015), effective Aug 19, 2026.

How has the price of NAYZILAM 5 MG NASAL SPRAY changed over time?

Over the history we have for it, the NADAC for NAYZILAM 5 MG NASAL SPRAY has risen 24.0%. It has been tracked across 336 weekly CMS publications since Mar 18, 2020.

What are the highest and lowest recorded NADAC prices for NAYZILAM 5 MG NASAL SPRAY?

Since Mar 18, 2020, the NADAC for NAYZILAM 5 MG NASAL SPRAY has ranged from a low of $263.8393 (Jan 20, 2021) to a high of $327.6376 (May 13, 2026), with a median of $299.4883 per EA.

Are there cheaper alternatives to NAYZILAM 5 MG NASAL SPRAY?

No other NADAC-published product currently shares the active ingredient and strength of NAYZILAM 5 MG NASAL SPRAY in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures NAYZILAM 5 MG NASAL SPRAY?

NAYZILAM 5 MG NASAL SPRAY (NDC 50474050015) is labeled by UCB, Inc., and CMS classifies it as a brand product.