Misoprostol
19 NDCs across 6 manufacturers|19 Generic,0 Brand
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The brand product was first FDA-approved on Dec 27, 1988, and the first generic was approved Jul 10, 2002. FDA's Orange Book lists 6 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $4 million on Misoprostol across 91,000 claims for 49,000 beneficiaries.
Misoprostol is available as 19 NDCs from 6 manufacturers (19 generic, 0 brand), with NADAC prices from $0.37 to $0.72 per EA — a 92% difference between cheapest and most expensive. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
19
19G / 0B
Manufacturers
6
competing in market
Price Spread
$0.37 – $0.72
per EA
7d Activity
avg -2.6% WoW · of 19 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Top supplier
GenBioPro, Inc. manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Prostaglandin E1 Analog class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
6 manufacturers producing MISOPROSTOL
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7189 per EA | -2.02% |
MISOPROSTOL 200 MCG TABLET | $0.7002 per EA | — |
MISOPROSTOL 200 MCG TABLET | $0.6822 per EA | — |
MISOPROSTOL 200 MCG TABLET | $0.5784 per EA | — |
MISOPROSTOL 100 MCG TABLET | $0.4645 per EA | -3.56% |
MISOPROSTOL 100 MCG TABLET | $0.4645 per EA | -3.56% |
MISOPROSTOL 100 MCG TABLET | $0.4645 per EA | -3.56% |
MISOPROSTOL 100 MCG TABLET | $0.4645 per EA | -3.56% |
MISOPROSTOL 100 MCG TABLET | $0.4645 per EA | -3.56% |
MISOPROSTOL 100 MCG TABLET | $0.3737 per EA | — |
MISOPROSTOL 100 MCG TABLET | $0.3737 per EA | — |
Frequently Asked Questions
When did Misoprostol become available as a generic?
FDA approved the first generic Misoprostol (ANDA) on Jul 10, 2002. The Orange Book currently lists 6 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Misoprostol?
In 2024, Medicare Part D spent $4 million on Misoprostol across 91,000 claims for 49,000 beneficiaries.
How many Misoprostol products are on the market?
The Misoprostol drug market contains 19 NDCs from 6 manufacturers — 19 generic and 0 brand products.
What is the price range for Misoprostol?
NADAC reference prices for Misoprostol range from $0.3737 to $0.7189 per EA — a 92% difference between cheapest and most expensive.
Which manufacturers make Misoprostol?
6 manufacturers list Misoprostol in NADAC. Ranked by number of NDCs, the largest are GenBioPro, Inc. (4), Mylan Pharmaceuticals Inc. (4), ANI Pharmaceuticals, Inc. (4), Lupin Pharmaceuticals Inc. (4), American Health Packaging (2).
How has the price of Misoprostol changed recently?
Over the past 7 days, 0 Misoprostol NDCs rose and 14 fell, with a market-wide average change of -2.6%.