Valproic Acid
8 NDCs across 8 manufacturers|8 Generic,0 Brand
Valproic Acid is used to treat alzheimer disease, bipolar disorder, epilepsy, absence epilepsy and complex partial epilepsy, per the National Library of Medicine's MED-RT classification.
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The brand product was first FDA-approved before 1982, and the first generic was approved Feb 28, 1986. FDA's Orange Book lists 2 AB-rated (therapeutically equivalent) products for this ingredient. In 2024, Medicare Part D spent $5 million on Valproic Acid across 107,000 claims for 20,000 beneficiaries.
Valproic Acid is available as 8 NDCs from 8 manufacturers (8 generic, 0 brand), with NADAC prices from $0.03 to $0.04 per ML — a 10% difference between cheapest and most expensive. Every pack size and labeler in this drug market is compared side-by-side below.
Total NDCs
8
8G / 0B
Manufacturers
8
competing in market
Price Spread
$0.03 – $0.04
per ML, 5 of 8 NDCs
7d Activity
avg +0.7% WoW · of 8 NDCs
Market Price Trend
Monthly average NADAC per unit, split by generic and brand.
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Move from the molecule page into the supplier, class, and trend views that create the strongest internal-link cluster for this market.
Top supplier
Upsher-Smith Laboratories LLC manufacturer profile
Open the supplier page for the manufacturer with the strongest footprint in this market.
Lead class
Anti-epileptic Agent class view
See how this market rolls up into the broader therapeutic class and compare other drugs in the same bucket.
Trend hub
Latest market trends
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Guide
How to interpret NADAC
Review the benchmark methodology behind the prices and spreads shown on this market page.
Manufacturer Breakdown
8 manufacturers producing VALPROIC ACID
| Drug ↕ | Price | 7d Change ↕ |
|---|---|---|
VALPROIC ACID 250 MG CAPSULE | $0.2426 per EA | +3.83% |
VALPROIC ACID 250 MG CAPSULE | $0.2426 per EA | +3.83% |
VALPROIC ACID 250 MG CAPSULE | $0.2426 per EA | +3.83% |
VALPROIC ACID 250 MG/5 ML SOLN | $0.0363 per ML | — |
VALPROIC ACID 250 MG/5 ML SOLN | $0.0332 per ML | -1.57% |
VALPROIC ACID 250 MG/5 ML SOLN | $0.0332 per ML | -1.57% |
VALPROIC ACID 250 MG/5 ML SOLN | $0.0332 per ML | -1.57% |
VALPROIC ACID 250 MG/5 ML SOLN | $0.0332 per ML | -1.57% |
Frequently Asked Questions
What is Valproic Acid used to treat?
Valproic Acid is used to treat alzheimer disease, bipolar disorder, epilepsy, absence epilepsy and complex partial epilepsy, per the National Library of Medicine's MED-RT classification.
When did Valproic Acid become available as a generic?
FDA approved the first generic Valproic Acid (ANDA) on Feb 28, 1986. The Orange Book currently lists 2 AB-rated products for this ingredient, meaning FDA considers them therapeutically equivalent to the brand.
How much does Medicare spend on Valproic Acid?
In 2024, Medicare Part D spent $5 million on Valproic Acid across 107,000 claims for 20,000 beneficiaries.
How many Valproic Acid products are on the market?
The Valproic Acid drug market contains 8 NDCs from 8 manufacturers — 8 generic and 0 brand products.
What is the price range for Valproic Acid?
NADAC reference prices for Valproic Acid range from $0.0332 to $0.0363 per ML — a 10% difference between cheapest and most expensive. 3 additional products are priced per different units (e.g. liquids per ML) and aren't directly comparable.
Which manufacturers make Valproic Acid?
8 manufacturers list Valproic Acid in NADAC. Ranked by number of NDCs, the largest are Upsher-Smith Laboratories LLC (1), Bionpharma Inc. (1), Actavis Pharma, Inc. (1), Lannett Company Inc. (1), ANI Pharmaceuticals, Inc. (1).
How has the price of Valproic Acid changed recently?
Over the past 7 days, 6 Valproic Acid NDCs rose and 8 fell, with a market-wide average change of +0.7%.