Product Information

VALPROIC ACID 250 MG/5 ML SOLN is a generic product labeled by PAI Holdings LLC, priced at $0.0337 per ML under NDC 00121067585. Its NADAC has been published 302 times since Nov 11, 2020.

FDA first approved this application on Dec 15, 2000. Its Orange Book therapeutic-equivalence code is AA.

VALPROIC ACID 250 MG/5 ML SOLN

VALPROIC ACID
$0.0337per ML

Strength

250 mg/5mL

Manufacturer

PAI Holdings LLC

NDC

00121067585

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

VALPROIC ACID

Approval Type

Generic (ANDA)

FDA Application

ANDA075379

FDA Approved

12/15/2000

TE Code

AA

On Market Since

4/11/2005

Pharmacological Classes

Anti-epileptic Agent
Decreased Central Nervous System Disorganized Electrical Activity
Mood Stabilizer

Price Statistics

The NADAC for VALPROIC ACID 250 MG/5 ML SOLN has been published 302 times since Nov 11, 2020, and over the history we have for it it has risen 78.5%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0337 per ML
All-time high$0.0363 (Nov 13, 2024)
All-time low$0.0170 (Apr 21, 2021)
52-week high$0.0340
52-week low$0.0325
Median price$0.0261
Average price$0.0260
Largest weekly change+25.7% (Jun 19, 2024)
Weeks tracked302
Tracking sinceNov 11, 2020

Price History

1W

+1.3%

1M

+1.3%

3M

+1.6%

6M

+0.2%

1Y

-0.2%

3Y

+48.7%

5Y

+80.6%

All

+78.5%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of VALPROIC ACID 250 MG/5 ML SOLN?

The current National Average Drug Acquisition Cost (NADAC) for VALPROIC ACID 250 MG/5 ML SOLN, manufactured by PAI Holdings LLC, is $0.0337 per ML (NDC 00121067585), effective Aug 19, 2026.

How has the price of VALPROIC ACID 250 MG/5 ML SOLN changed over time?

Over the history we have for it, the NADAC for VALPROIC ACID 250 MG/5 ML SOLN has risen 78.5%. It has been tracked across 302 weekly CMS publications since Nov 11, 2020.

What are the highest and lowest recorded NADAC prices for VALPROIC ACID 250 MG/5 ML SOLN?

Since Nov 11, 2020, the NADAC for VALPROIC ACID 250 MG/5 ML SOLN has ranged from a low of $0.0170 (Apr 21, 2021) to a high of $0.0363 (Nov 13, 2024), with a median of $0.0261 per ML.

Are there cheaper alternatives to VALPROIC ACID 250 MG/5 ML SOLN?

2 manufacturers publish a NADAC-priced product with the same active ingredient and strength as VALPROIC ACID 250 MG/5 ML SOLN in a comparable dosage form, but none are currently priced below it.

Who manufactures VALPROIC ACID 250 MG/5 ML SOLN?

VALPROIC ACID 250 MG/5 ML SOLN (NDC 00121067585) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.