Product Information
JANUMET 50-500 MG TABLET is a brand product labeled by Merck Sharp & Dohme LLC, priced at $5.2828 per EA under NDC 00006057561. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Mar 30, 2007. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
500; 50 mg/1; mg/1
Manufacturer
Merck Sharp & Dohme LLCNDC
00006057561
Classification
Brand
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
METFORMIN HYDROCHLORIDE; SITAGLIPTIN PHOSPHATEApproval Type
New Drug (NDA)
FDA Application
NDA022044FDA Approved
3/30/2007
TE Code
AB
On Market Since
3/30/2007
Pharmacological Classes
Price Statistics
The NADAC for JANUMET 50-500 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 26.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $5.2828 per EA |
|---|---|
| All-time high | $9.1837 (Jun 12, 2024) |
| All-time low | $4.1751 (Nov 28, 2013) |
| 52-week high | $5.2846 |
| 52-week low | $5.2828 |
| Median price | $6.8793 |
| Average price | $6.8307 |
| Largest weekly change | -42.4% (Jan 1, 2025) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of JANUMET 50-500 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for JANUMET 50-500 MG TABLET, manufactured by Merck Sharp & Dohme LLC, is $5.2828 per EA (NDC 00006057561), effective Aug 19, 2026.
How has the price of JANUMET 50-500 MG TABLET changed over time?
Over the history we have for it, the NADAC for JANUMET 50-500 MG TABLET has risen 26.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for JANUMET 50-500 MG TABLET?
Since Nov 28, 2013, the NADAC for JANUMET 50-500 MG TABLET has ranged from a low of $4.1751 (Nov 28, 2013) to a high of $9.1837 (Jun 12, 2024), with a median of $6.8793 per EA.
Are there cheaper alternatives to JANUMET 50-500 MG TABLET?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as JANUMET 50-500 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures JANUMET 50-500 MG TABLET?
JANUMET 50-500 MG TABLET (NDC 00006057561) is labeled by Merck Sharp & Dohme LLC, and CMS classifies it as a brand product.