Therapeutic Classes/Dipeptidyl Peptidase 4 Inhibitor

Dipeptidyl Peptidase 4 Inhibitor

100 drugs across 10 manufacturers|23 Generic,77 Brand

The Dipeptidyl Peptidase 4 Inhibitor class contains 100 NDCs from 10 manufacturers (23 generic, 77 brand), at an average NADAC of $8.59 per unit. Every drug, manufacturer, and price in this FDA-defined pharmacologic class is listed below.

Total Drugs

100

23G / 77B

Manufacturers

Avg $8.5940/unit

Avg 7d Change

-0.14%

Across 72 drugs with changes

7d Activity

41↑31↓28 flat

of 100 total drugs

Class Price Trend

Monthly average NADAC price per unit, split by generic and brand

Manufacturer Breakdown

10 manufacturers producing drugs in this therapeutic class

Merck Sharp & Dohme LLC

31 drugs

$9.6361

avg/unit

Boehringer Ingelheim Pharmaceuticals Inc.

27 drugs

$10.6242

avg/unit

Takeda Pharmaceuticals America, Inc.

7 drugs

$10.8329

avg/unit

Zydus Pharmaceuticals (USA) Inc.

7 drugs

$7.9105

avg/unit

Padagis Israel Pharmaceuticals Ltd

7 drugs

$4.3394

avg/unit

Mylan Pharmaceuticals Inc.

6 drugs

$3.1701

avg/unit

AstraZeneca Pharmaceuticals LP

5 drugs

$13.9674

avg/unit

Aurobindo Pharma Limited

4 drugs

$1.0916

avg/unit

Glenmark Pharmaceuticals Inc., USA

4 drugs

$1.0916

avg/unit

Dr. Reddy's Laboratories Inc.

2 drugs

$7.3270

avg/unit

Drug Portfolio

100 drugs total, 100 shown

Drug ↕	NDC	Price	7d Change ↕	Class	Market Outlier	Manufacturer ↕
STEGLUJAN 15-100 MG TABLET ertugliflozin and sitagliptin	00006536803	$17.5864 per EA	+0.28%	Brand	—	Merck Sharp & Dohme LLC
STEGLUJAN 15-100 MG TABLET ertugliflozin and sitagliptin	00006536806	$17.5864 per EA	+0.28%	Brand	—	Merck Sharp & Dohme LLC
STEGLUJAN 5-100 MG TABLET ertugliflozin and sitagliptin	00006536703	$17.4091 per EA	—	Brand	—	Merck Sharp & Dohme LLC
STEGLUJAN 5-100 MG TABLET ertugliflozin and sitagliptin	00006536706	$17.4091 per EA	—	Brand	—	Merck Sharp & Dohme LLC
JENTADUETO XR 5 MG-1,000 MG TB linagliptin and metformin hydrochloride	00597027533	$16.9470 per EA	0.00%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO XR 5 MG-1,000 MG TB linagliptin and metformin hydrochloride	00597027581	$16.9470 per EA	0.00%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRADJENTA 5 MG TABLET linagliptin	00597014030	$16.7982 per EA	+0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRADJENTA 5 MG TABLET linagliptin	00597014061	$16.7982 per EA	+0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRADJENTA 5 MG TABLET linagliptin	00597014090	$16.7982 per EA	+0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
KOMBIGLYZE XR 5-1,000 MG TAB SAXAGLIPTIN AND METFORMIN HYDROCHLORIDE	00310614530	$15.5404 per EA	—	Brand	—	AstraZeneca Pharmaceuticals LP
ONGLYZA 5 MG TABLET SAXAGLIPTIN	00310610530	$15.5149 per EA	—	Brand	High Outlier	AstraZeneca Pharmaceuticals LP
ONGLYZA 5 MG TABLET SAXAGLIPTIN	00310610590	$15.5149 per EA	—	Brand	High Outlier	AstraZeneca Pharmaceuticals LP
KOMBIGLYZE XR 5-500 MG TABLET SAXAGLIPTIN AND METFORMIN HYDROCHLORIDE	00310613530	$15.4800 per EA	—	Brand	—	AstraZeneca Pharmaceuticals LP
JANUVIA 100 MG TABLET sitagliptin	00006027702	$14.4383 per EA	—	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 100 MG TABLET sitagliptin	00006027733	$13.7554 per EA	—	Brand	—	Merck Sharp & Dohme LLC
NESINA 12.5 MG TABLET alogliptin	64764012530	$13.1377 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
NESINA 25 MG TABLET alogliptin	64764025030	$13.0731 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
OSENI 25-30 MG TABLET alogliptin and pioglitazone	64764025303	$12.3977 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
OSENI 25-45 MG TABLET alogliptin and pioglitazone	64764025403	$12.0589 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
OSENI 25-15 MG TABLET alogliptin and pioglitazone	64764025103	$12.0092 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
TRIJARDY XR 10-5-1,000 MG TAB empagliflozin, linagliptin, metformin hydrochloride	00597038013	$11.2774 per EA	-0.08%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRIJARDY XR 10-5-1,000 MG TAB empagliflozin, linagliptin, metformin hydrochloride	00597038068	$11.2774 per EA	-0.08%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
GLYXAMBI 10 MG-5 MG TABLET empagliflozin and linagliptin	00597018230	$11.2437 per EA	-0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
GLYXAMBI 10 MG-5 MG TABLET empagliflozin and linagliptin	00597018239	$11.2437 per EA	-0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
GLYXAMBI 10 MG-5 MG TABLET empagliflozin and linagliptin	00597018290	$11.2437 per EA	-0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRIJARDY XR 25-5-1,000 MG TAB empagliflozin, linagliptin, metformin hydrochloride	00597039013	$11.2386 per EA	+0.04%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRIJARDY XR 25-5-1,000 MG TAB empagliflozin, linagliptin, metformin hydrochloride	00597039071	$11.2386 per EA	+0.04%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
GLYXAMBI 25 MG-5 MG TABLET empagliflozin and linagliptin	00597016430	$11.1994 per EA	+0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
GLYXAMBI 25 MG-5 MG TABLET empagliflozin and linagliptin	00597016439	$11.1994 per EA	+0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
GLYXAMBI 25 MG-5 MG TABLET empagliflozin and linagliptin	00597016490	$11.1994 per EA	+0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JANUMET XR 100-1,000 MG TABLET sitagliptin and metformin hydrochloride	00006008131	$10.5559 per EA	0.00%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 100-1,000 MG TABLET sitagliptin and metformin hydrochloride	00006008154	$10.5559 per EA	0.00%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 100-1,000 MG TABLET sitagliptin and metformin hydrochloride	00006008182	$10.5559 per EA	0.00%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 50 MG TABLET sitagliptin	00006011228	$10.5521 per EA	0.00%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 50 MG TABLET sitagliptin	00006011231	$10.5521 per EA	0.00%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 50 MG TABLET sitagliptin	00006011254	$10.5521 per EA	0.00%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 100 MG TABLET sitagliptin	00006027728	$10.5518 per EA	-0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 100 MG TABLET sitagliptin	00006027731	$10.5518 per EA	-0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 100 MG TABLET sitagliptin	00006027754	$10.5518 per EA	-0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 100 MG TABLET sitagliptin	00006027782	$10.5518 per EA	-0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 25 MG TABLET sitagliptin	00006022128	$10.5436 per EA	+0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 25 MG TABLET sitagliptin	00006022131	$10.5436 per EA	+0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUVIA 25 MG TABLET sitagliptin	00006022154	$10.5436 per EA	+0.01%	Brand	—	Merck Sharp & Dohme LLC
ZITUVIO 100 MG TABLET Sitagliptin	70710124203	$10.0823 per EA	-0.06%	Brand	—	Zydus Pharmaceuticals (USA) Inc.
ZITUVIMET XR 100-1,000 MG TAB sitagliptin and metformin hydrochloride	70710180603	$10.0792 per EA	+0.10%	Brand	—	Zydus Pharmaceuticals (USA) Inc.
ZITUVIO 25 MG TABLET Sitagliptin	70710124003	$10.0542 per EA	-0.08%	Brand	—	Zydus Pharmaceuticals (USA) Inc.
ZITUVIO 50 MG TABLET Sitagliptin	70710124103	$10.0496 per EA	+0.13%	Brand	—	Zydus Pharmaceuticals (USA) Inc.
SAXAGLIPTIN-METFORMIN ER 5-1,000 MG TABLET saxagliptin and metformin	00378817793	$9.6470 per EA	-2.67%	Generic	—	Mylan Pharmaceuticals Inc.
SAXAGLIPTIN-METFORMIN ER 5-1,000 MG TABLET Saxagliptin and Metformin Hydrochloride	43598061930	$9.6470 per EA	-2.67%	Generic	—	Dr. Reddy's Laboratories Inc.
JENTADUETO XR 2.5 MG-1,000 MG linagliptin and metformin hydrochloride	00597027073	$8.4695 per EA	-0.03%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO XR 2.5 MG-1,000 MG linagliptin and metformin hydrochloride	00597027094	$8.4695 per EA	-0.03%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO 2.5 MG-850 MG TAB linagliptin and metformin hydrochloride	00597014718	$8.4543 per EA	+0.10%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO 2.5 MG-850 MG TAB linagliptin and metformin hydrochloride	00597014760	$8.4543 per EA	+0.10%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO 2.5 MG-500 MG TAB linagliptin and metformin hydrochloride	00597014618	$8.4429 per EA	-0.05%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO 2.5 MG-500 MG TAB linagliptin and metformin hydrochloride	00597014660	$8.4429 per EA	-0.05%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO 2.5 MG-1,000 MG TAB linagliptin and metformin hydrochloride	00597014818	$8.4388 per EA	-0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JENTADUETO 2.5 MG-1,000 MG TAB linagliptin and metformin hydrochloride	00597014860	$8.4388 per EA	-0.01%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
KOMBIGLYZE XR 2.5-1,000 MG TAB SAXAGLIPTIN AND METFORMIN HYDROCHLORIDE	00310612560	$7.7865 per EA	—	Brand	—	AstraZeneca Pharmaceuticals LP
KAZANO 12.5-500 MG TABLET alogliptin and metformin hydrochloride	64764033560	$6.5885 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
KAZANO 12.5-1,000 MG TABLET alogliptin and metformin hydrochloride	64764033760	$6.5654 per EA	—	Brand	—	Takeda Pharmaceuticals America, Inc.
ALOGLIPTIN-PIOGLIT 25-30 MG TB Alogliptin Benzoate and Pioglitazone hydrochloride	45802040265	$5.7169 per EA	—	Generic	—	Padagis Israel Pharmaceuticals Ltd
TRIJARDY XR 5-2.5-1,000 MG TAB empagliflozin, linagliptin, metformin hydrochloride	00597039523	$5.6686 per EA	+0.08%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRIJARDY XR 5-2.5-1,000 MG TAB empagliflozin, linagliptin, metformin hydrochloride	00597039582	$5.6686 per EA	+0.08%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRIJARDY XR 12.5-2.5-1,000 MG empagliflozin, linagliptin, metformin hydrochloride	00597038577	$5.6277 per EA	+0.04%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
TRIJARDY XR 12.5-2.5-1,000 MG empagliflozin, linagliptin, metformin hydrochloride	00597038586	$5.6277 per EA	+0.04%	Brand	—	Boehringer Ingelheim Pharmaceuticals Inc.
JANUMET 50-500 MG TABLET SITAGLIPTIN and METFORMIN HYDROCHLORIDE	00006057561	$5.2840 per EA	+0.02%	Brand	—	Merck Sharp & Dohme LLC
JANUMET 50-500 MG TABLET SITAGLIPTIN and METFORMIN HYDROCHLORIDE	00006057562	$5.2840 per EA	+0.02%	Brand	—	Merck Sharp & Dohme LLC
JANUMET 50-500 MG TABLET SITAGLIPTIN and METFORMIN HYDROCHLORIDE	00006057582	$5.2840 per EA	+0.02%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 50-500 MG TABLET sitagliptin and metformin hydrochloride	00006007861	$5.2830 per EA	+0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 50-500 MG TABLET sitagliptin and metformin hydrochloride	00006007862	$5.2830 per EA	+0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 50-500 MG TABLET sitagliptin and metformin hydrochloride	00006007882	$5.2830 per EA	+0.01%	Brand	—	Merck Sharp & Dohme LLC
JANUMET 50-1,000 MG TABLET SITAGLIPTIN and METFORMIN HYDROCHLORIDE	00006057761	$5.2793 per EA	-0.04%	Brand	—	Merck Sharp & Dohme LLC
JANUMET 50-1,000 MG TABLET SITAGLIPTIN and METFORMIN HYDROCHLORIDE	00006057762	$5.2793 per EA	-0.04%	Brand	—	Merck Sharp & Dohme LLC
JANUMET 50-1,000 MG TABLET SITAGLIPTIN and METFORMIN HYDROCHLORIDE	00006057782	$5.2793 per EA	-0.04%	Brand	—	Merck Sharp & Dohme LLC
ALOGLIPTIN 6.25 MG TABLET Alogliptin	45802008765	$5.2782 per EA	+1.89%	Generic	—	Padagis Israel Pharmaceuticals Ltd
JANUMET XR 50-1,000 MG TABLET sitagliptin and metformin hydrochloride	00006008061	$5.2781 per EA	+0.04%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 50-1,000 MG TABLET sitagliptin and metformin hydrochloride	00006008062	$5.2781 per EA	+0.04%	Brand	—	Merck Sharp & Dohme LLC
JANUMET XR 50-1,000 MG TABLET sitagliptin and metformin hydrochloride	00006008082	$5.2781 per EA	+0.04%	Brand	—	Merck Sharp & Dohme LLC
ZITUVIMET 50-500 MG TABLET Sitagliptin and Metformin Hydrochloride	70710178606	$5.0582 per EA	—	Brand	—	Zydus Pharmaceuticals (USA) Inc.
ZITUVIMET 50-1,000 MG TABLET Sitagliptin and Metformin Hydrochloride	70710178706	$5.0305 per EA	+0.02%	Brand	—	Zydus Pharmaceuticals (USA) Inc.
ZITUVIMET XR 50-1,000 MG TABLET sitagliptin and metformin hydrochloride	70710180506	$5.0193 per EA	0.00%	Brand	—	Zydus Pharmaceuticals (USA) Inc.
SAXAGLIPTIN-METFORMIN ER 2.5-1,000 MG TABLET saxagliptin and metformin	00378817691	$5.0070 per EA	+0.55%	Generic	—	Mylan Pharmaceuticals Inc.
SAXAGLIPTIN-METFORMIN ER 2.5-1,000 MG TABLET Saxagliptin and Metformin Hydrochloride	43598061860	$5.0070 per EA	+0.55%	Generic	—	Dr. Reddy's Laboratories Inc.
ALOGLIPTIN 12.5 MG TABLET Alogliptin	45802010365	$4.9568 per EA	-1.93%	Generic	—	Padagis Israel Pharmaceuticals Ltd
ALOGLIPTIN 25 MG TABLET Alogliptin	45802015065	$4.9069 per EA	-0.33%	Generic	—	Padagis Israel Pharmaceuticals Ltd
ALOGLIPTIN-PIOGLIT 25-15 MG TB Alogliptin Benzoate and Pioglitazone hydrochloride	45802035165	$4.7314 per EA	—	Generic	—	Padagis Israel Pharmaceuticals Ltd
ALOGLIPTIN-METFORMIN 12.5-1000 alogliptin and metformin hydrochloride	45802021172	$2.4649 per EA	-1.17%	Generic	—	Padagis Israel Pharmaceuticals Ltd
ALOGLIPTIN-METFORMIN 12.5-500 alogliptin and metformin hydrochloride	45802016972	$2.3206 per EA	+0.87%	Generic	—	Padagis Israel Pharmaceuticals Ltd
SAXAGLIPTIN HCL 2.5 MG TABLET saxagliptin	00378470577	$1.1445 per EA	+0.35%	Generic	—	Mylan Pharmaceuticals Inc.
SAXAGLIPTIN HCL 2.5 MG TABLET saxagliptin	00378470593	$1.1445 per EA	+0.35%	Generic	—	Mylan Pharmaceuticals Inc.
SAXAGLIPTIN HCL 2.5 MG TABLET Saxagliptin	65862082530	$1.1445 per EA	+0.35%	Generic	—	Aurobindo Pharma Limited
SAXAGLIPTIN HCL 2.5 MG TABLET Saxagliptin	65862082590	$1.1445 per EA	+0.35%	Generic	—	Aurobindo Pharma Limited
SAXAGLIPTIN HCL 2.5 MG TABLET SAXAGLIPTIN	68462072630	$1.1445 per EA	+0.35%	Generic	—	Glenmark Pharmaceuticals Inc., USA
SAXAGLIPTIN HCL 2.5 MG TABLET SAXAGLIPTIN	68462072690	$1.1445 per EA	+0.35%	Generic	—	Glenmark Pharmaceuticals Inc., USA
SAXAGLIPTIN HCL 5 MG TABLET saxagliptin	00378470677	$1.0387 per EA	-1.03%	Generic	—	Mylan Pharmaceuticals Inc.
SAXAGLIPTIN HCL 5 MG TABLET saxagliptin	00378470693	$1.0387 per EA	-1.03%	Generic	—	Mylan Pharmaceuticals Inc.
SAXAGLIPTIN HCL 5 MG TABLET Saxagliptin	65862082630	$1.0387 per EA	-1.03%	Generic	—	Aurobindo Pharma Limited
SAXAGLIPTIN HCL 5 MG TABLET Saxagliptin	65862082690	$1.0387 per EA	-1.03%	Generic	—	Aurobindo Pharma Limited
SAXAGLIPTIN HCL 5 MG TABLET SAXAGLIPTIN	68462072730	$1.0387 per EA	-1.03%	Generic	—	Glenmark Pharmaceuticals Inc., USA
SAXAGLIPTIN HCL 5 MG TABLET SAXAGLIPTIN	68462072790	$1.0387 per EA	-1.03%	Generic	—	Glenmark Pharmaceuticals Inc., USA

Follow this class across the site

These links connect the therapeutic class page to the specific suppliers, markets, and trend surfaces that help users keep exploring.

Top supplier

Merck Sharp & Dohme LLC manufacturer profile

Review the supplier with the strongest product footprint inside this therapeutic class.

Lead market

sitagliptin market page

Move from the therapeutic class into the molecule that appears most often in this class-specific portfolio.

Trend hub

Latest trend hub

Compare this class against the rest of the weekly NADAC trend surface.

Guide

Understanding NADAC pricing

Use the explainer when you need a plain-English refresher on how these class-level numbers are published and interpreted.

Frequently Asked Questions

How many drugs are in the Dipeptidyl Peptidase 4 Inhibitor class?

The Dipeptidyl Peptidase 4 Inhibitor class contains 100 NDCs from 10 manufacturers — 23 generic and 77 brand products.

What is the average price of Dipeptidyl Peptidase 4 Inhibitor drugs?

The average NADAC for the Dipeptidyl Peptidase 4 Inhibitor class is $8.5940 per unit across 100 NDCs.

Is generic cheaper than brand in the Dipeptidyl Peptidase 4 Inhibitor class?

Among products priced per EA, the average generic NADAC in this class is $3.1645, versus $10.2158 for brand — brand products average about 3.2× the generic price.

Which manufacturers make Dipeptidyl Peptidase 4 Inhibitor drugs?

10 manufacturers make drugs in the Dipeptidyl Peptidase 4 Inhibitor class. Ranked by number of NDCs, the largest are Merck Sharp & Dohme LLC (31), Boehringer Ingelheim Pharmaceuticals Inc. (27), Takeda Pharmaceuticals America, Inc. (7), Zydus Pharmaceuticals (USA) Inc. (7), Padagis Israel Pharmaceuticals Ltd (7).

How has Dipeptidyl Peptidase 4 Inhibitor pricing changed recently?

Over the past 7 days, 41 NDCs in this class rose and 31 fell, with a class-wide average change of -0.1%.