This NDC is on FDA's drug shortage list (posted Dec 15, 2021)
Reported reason: Demand increase for the drug
Product Information
DEPO-MEDROL 40 MG/ML VIAL is a brand product labeled by Pharmacia & Upjohn Company LLC, priced at $6.8789 per ML under NDC 00009307301. Its NADAC has been published 417 times since Nov 28, 2013.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
40 mg/mL
Manufacturer
Pharmacia & Upjohn Company LLCNDC
00009307301
Classification
Brand
Dosage Form
INJECTION, SUSPENSION
Route
INTRA-ARTICULAR; INTRALESIONAL; INTRAMUSCULAR; SOFT TISSUE
Effective Date
8/19/2026
Active Ingredients
METHYLPREDNISOLONE ACETATEApproval Type
New Drug (NDA)
FDA Application
NDA011757FDA Approved
Before 1982
TE Code
AB
On Market Since
5/28/1959
Pharmacological Classes
Price Statistics
The NADAC for DEPO-MEDROL 40 MG/ML VIAL has been published 417 times since Nov 28, 2013, and over the history we have for it it has risen 24.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $6.8789 per ML |
|---|---|
| All-time high | $11.0670 (Jul 11, 2018) |
| All-time low | $5.0640 (Nov 18, 2015) |
| 52-week high | $7.5767 |
| 52-week low | $6.6865 |
| Median price | $7.2250 |
| Average price | $7.6901 |
| Largest weekly change | +56.5% (Feb 18, 2015) |
| Weeks tracked | 417 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 16% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of DEPO-MEDROL 40 MG/ML VIAL?
The current National Average Drug Acquisition Cost (NADAC) for DEPO-MEDROL 40 MG/ML VIAL, manufactured by Pharmacia & Upjohn Company LLC, is $6.8789 per ML (NDC 00009307301), effective Aug 19, 2026.
How has the price of DEPO-MEDROL 40 MG/ML VIAL changed over time?
Over the history we have for it, the NADAC for DEPO-MEDROL 40 MG/ML VIAL has risen 24.2%. It has been tracked across 417 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for DEPO-MEDROL 40 MG/ML VIAL?
Since Nov 28, 2013, the NADAC for DEPO-MEDROL 40 MG/ML VIAL has ranged from a low of $5.0640 (Nov 18, 2015) to a high of $11.0670 (Jul 11, 2018), with a median of $7.2250 per ML.
Are there cheaper alternatives to DEPO-MEDROL 40 MG/ML VIAL?
Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, METHYLPREDNISOLONE 400 MG/10 ML, is $5.8078 per ML — about 16% below DEPO-MEDROL 40 MG/ML VIAL.
Who manufactures DEPO-MEDROL 40 MG/ML VIAL?
DEPO-MEDROL 40 MG/ML VIAL (NDC 00009307301) is labeled by Pharmacia & Upjohn Company LLC, and CMS classifies it as a brand product.
Is DEPO-MEDROL 40 MG/ML VIAL in shortage?
Yes — NDC 00009307301 is currently listed in FDA's drug shortage database (posted Dec 15, 2021). Reported reason: Demand increase for the drug.