Product Information

AMBIEN CR 12.5 MG TABLET is a brand product labeled by Sanofi-Aventis U.S. LLC, priced at $22.5920 per EA under NDC 00024552131. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Sep 2, 2005. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the zolpidem tartrate market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

AMBIEN CR 12.5 MG TABLET

zolpidem tartrate
$22.5920per EA
Discontinued
High Outlier
DEA Schedule CIV

Strength

12.5 mg/1

NDC

00024552131

Classification

Brand

Dosage Form

TABLET, COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

ZOLPIDEM TARTRATE

Approval Type

New Drug (NDA)

FDA Application

NDA021774

FDA Approved

9/2/2005

TE Code

AB

On Market Since

9/19/2005

Pharmacological Classes

Central Nervous System Depression
GABA A Receptor Positive Modulators
gamma-Aminobutyric Acid A Receptor Positive Modulator

Price Statistics

The NADAC for AMBIEN CR 12.5 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 131.3%. The table below summarizes its recorded NADAC range and movement.

Current price$22.5920 per EA
All-time high$22.5920 (Aug 19, 2026)
All-time low$9.5488 (Feb 19, 2014)
52-week high$22.5920
52-week low$20.5394
Median price$17.9230
Average price$17.2532
Largest weekly change+10.0% (Oct 14, 2015)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+0.1%

1M

+0.1%

3M

+0.1%

6M

+0.1%

1Y

+9.5%

3Y

+10.2%

5Y

+21.3%

All

+131.3%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 99% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of AMBIEN CR 12.5 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for AMBIEN CR 12.5 MG TABLET, manufactured by Sanofi-Aventis U.S. LLC, is $22.5920 per EA (NDC 00024552131), effective Aug 19, 2026.

How has the price of AMBIEN CR 12.5 MG TABLET changed over time?

Over the history we have for it, the NADAC for AMBIEN CR 12.5 MG TABLET has risen 131.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for AMBIEN CR 12.5 MG TABLET?

Since Nov 28, 2013, the NADAC for AMBIEN CR 12.5 MG TABLET has ranged from a low of $9.5488 (Feb 19, 2014) to a high of $22.5920 (Aug 19, 2026), with a median of $17.9230 per EA.

Are there cheaper alternatives to AMBIEN CR 12.5 MG TABLET?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, ZOLPIDEM TART ER 12.5 MG TAB, is $0.1130 per EA — about 99% below AMBIEN CR 12.5 MG TABLET.

Who manufactures AMBIEN CR 12.5 MG TABLET?

AMBIEN CR 12.5 MG TABLET (NDC 00024552131) is labeled by Sanofi-Aventis U.S. LLC, and CMS classifies it as a brand product.