Product Information

ZOLOFT 50 MG TABLET is a brand product labeled by Roerig, priced at $14.8841 per EA under NDC 00049490030. Its NADAC has been published 657 times since Nov 28, 2013.

The High Outlier badge above means this manufacturer's average price in the sertraline hydrochloride market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ZOLOFT 50 MG TABLET

sertraline hydrochloride
$14.8841per EA
High Outlier

Strength

50 mg/1

Manufacturer

Roerig

NDC

00049490030

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Last Updated

6/17/2026

Active Ingredients

SERTRALINE HYDROCHLORIDE

Approval Type

New Drug (NDA)

FDA Application

NDA019839

On Market Since

2/11/1992

Pharmacological Classes

Cytochrome P450 2D6 Inhibitors
Serotonin Reuptake Inhibitor
Serotonin Uptake Inhibitors

Price Statistics

The NADAC for ZOLOFT 50 MG TABLET has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 200.8%. The table below summarizes its recorded NADAC range and movement.

Current price$14.8841 per EA
All-time high$14.9258 (May 13, 2026)
All-time low$4.9488 (Nov 28, 2013)
52-week high$14.9258
52-week low$14.1567
Median price$11.2340
Average price$10.6050
Largest weekly change+9.4% (Jan 6, 2016)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

+0.2%

3M

-0.3%

6M

+4.7%

1Y

+5.1%

3Y

+12.4%

5Y

+26.3%

All

+200.8%

Generic Alternatives

The matcher finds 3 NADAC-published products sharing this drug's active ingredient, strength, and dosage form across 3 manufacturers (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 100% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ZOLOFT 50 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ZOLOFT 50 MG TABLET, manufactured by Roerig, is $14.8841 per EA (NDC 00049490030), effective Jun 24, 2026.

How has the price of ZOLOFT 50 MG TABLET changed over time?

Over the history we have for it, the NADAC for ZOLOFT 50 MG TABLET has risen 200.8%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ZOLOFT 50 MG TABLET?

Since Nov 28, 2013, the NADAC for ZOLOFT 50 MG TABLET has ranged from a low of $4.9488 (Nov 28, 2013) to a high of $14.9258 (May 13, 2026), with a median of $11.2340 per EA.

Are there cheaper alternatives to ZOLOFT 50 MG TABLET?

Yes. 3 NADAC-published products share the same active ingredient, strength, and dosage form. The lowest-priced option, SERTRALINE HCL 50 MG TABLET, is $0.0343 per EA — about 100% below ZOLOFT 50 MG TABLET.

Who manufactures ZOLOFT 50 MG TABLET?

ZOLOFT 50 MG TABLET (NDC 00049490030) is labeled by Roerig, and CMS classifies it as a brand product.