Product Information

METHADONE 10 MG/5 ML SOLUTION is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.1024 per ML under NDC 00054355663. Its NADAC has been published 191 times since Nov 28, 2013.

FDA first approved this application on Aug 30, 1982. Its Orange Book therapeutic-equivalence code is AA.

METHADONE 10 MG/5 ML SOLUTION

Methadone Hydrochloride
$0.1024per ML
DEA Schedule CII

Strength

10 mg/5mL

NDC

00054355663

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

7/23/2025

Active Ingredients

METHADONE HYDROCHLORIDE

Approval Type

Generic (ANDA)

FDA Application

ANDA087997

FDA Approved

8/30/1982

TE Code

AA

On Market Since

8/30/1982

Pharmacological Classes

Full Opioid Agonists
Opioid Agonist

Price Statistics

The NADAC for METHADONE 10 MG/5 ML SOLUTION has been published 191 times since Nov 28, 2013, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$0.1024 per ML
All-time high$0.1110 (Dec 16, 2015)
All-time low$0.0982 (Dec 18, 2024)
52-week high$0.1024
52-week low$0.1024
Median price$0.1097
Average price$0.1064
Largest weekly change-11.6% (Dec 18, 2024)
Weeks tracked191
Tracking sinceNov 28, 2013

Price History

1W

N/A

1M

N/A

3M

0.0%

6M

0.0%

1Y

0.0%

3Y

-7.8%

5Y

-7.8%

All

-1.9%

Last surveyed Jul 15, 2026 — this NDC no longer appears in the current weekly NADAC file.

Generic Alternatives

No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Methadone Hydrochloride market page.

Lowest-Cost Alternatives

No alternatives available

No alternatives found with the same active ingredient and strength in a comparable dosage form.

Frequently asked questions

What is the NADAC price of METHADONE 10 MG/5 ML SOLUTION?

The current National Average Drug Acquisition Cost (NADAC) for METHADONE 10 MG/5 ML SOLUTION, manufactured by Hikma Pharmaceuticals USA Inc., is $0.1024 per ML (NDC 00054355663), effective Jul 15, 2026.

How has the price of METHADONE 10 MG/5 ML SOLUTION changed over time?

Over the history we have for it, the NADAC for METHADONE 10 MG/5 ML SOLUTION has held within roughly two percent of its current level. It has been tracked across 191 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for METHADONE 10 MG/5 ML SOLUTION?

Since Nov 28, 2013, the NADAC for METHADONE 10 MG/5 ML SOLUTION has ranged from a low of $0.0982 (Dec 18, 2024) to a high of $0.1110 (Dec 16, 2015), with a median of $0.1097 per ML.

Are there cheaper alternatives to METHADONE 10 MG/5 ML SOLUTION?

No other NADAC-published product currently shares the active ingredient and strength of METHADONE 10 MG/5 ML SOLUTION in a comparable dosage form, so no direct lower-cost alternative is listed.

Who manufactures METHADONE 10 MG/5 ML SOLUTION?

METHADONE 10 MG/5 ML SOLUTION (NDC 00054355663) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.