Product Information
METHADONE 10 MG/5 ML SOLUTION is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.1024 per ML under NDC 00054355663. Its NADAC has been published 191 times since Nov 28, 2013.
FDA first approved this application on Aug 30, 1982. Its Orange Book therapeutic-equivalence code is AA.
Strength
10 mg/5mL
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00054355663
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
7/23/2025
Active Ingredients
METHADONE HYDROCHLORIDEApproval Type
Generic (ANDA)
FDA Application
ANDA087997FDA Approved
8/30/1982
TE Code
AA
On Market Since
8/30/1982
Pharmacological Classes
Price Statistics
The NADAC for METHADONE 10 MG/5 ML SOLUTION has been published 191 times since Nov 28, 2013, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.1024 per ML |
|---|---|
| All-time high | $0.1110 (Dec 16, 2015) |
| All-time low | $0.0982 (Dec 18, 2024) |
| 52-week high | $0.1024 |
| 52-week low | $0.1024 |
| Median price | $0.1097 |
| Average price | $0.1064 |
| Largest weekly change | -11.6% (Dec 18, 2024) |
| Weeks tracked | 191 |
| Tracking since | Nov 28, 2013 |
1W
N/A
1M
N/A
3M
0.0%
6M
0.0%
1Y
0.0%
3Y
-7.8%
5Y
-7.8%
All
-1.9%
Last surveyed Jul 15, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the Methadone Hydrochloride market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Hikma Pharmaceuticals USA Inc. manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Methadone Hydrochloride market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Opioid Agonist class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of METHADONE 10 MG/5 ML SOLUTION?
The current National Average Drug Acquisition Cost (NADAC) for METHADONE 10 MG/5 ML SOLUTION, manufactured by Hikma Pharmaceuticals USA Inc., is $0.1024 per ML (NDC 00054355663), effective Jul 15, 2026.
How has the price of METHADONE 10 MG/5 ML SOLUTION changed over time?
Over the history we have for it, the NADAC for METHADONE 10 MG/5 ML SOLUTION has held within roughly two percent of its current level. It has been tracked across 191 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for METHADONE 10 MG/5 ML SOLUTION?
Since Nov 28, 2013, the NADAC for METHADONE 10 MG/5 ML SOLUTION has ranged from a low of $0.0982 (Dec 18, 2024) to a high of $0.1110 (Dec 16, 2015), with a median of $0.1097 per ML.
Are there cheaper alternatives to METHADONE 10 MG/5 ML SOLUTION?
No other NADAC-published product currently shares the active ingredient and strength of METHADONE 10 MG/5 ML SOLUTION in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures METHADONE 10 MG/5 ML SOLUTION?
METHADONE 10 MG/5 ML SOLUTION (NDC 00054355663) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.