Product Information
LEUCOVORIN CALCIUM 5 MG TAB is a generic product labeled by Hikma Pharmaceuticals USA Inc., priced at $0.3430 per EA under NDC 00054449625. Its NADAC has been published 665 times since Nov 28, 2013.
FDA first approved this application on Feb 22, 1993. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
5 mg/1
Manufacturer
Hikma Pharmaceuticals USA Inc.NDC
00054449625
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
8/19/2026
Active Ingredients
LEUCOVORIN CALCIUMApproval Type
Generic (ANDA)
FDA Application
ANDA072733FDA Approved
2/22/1993
TE Code
AB
On Market Since
2/22/1993
Pharmacological Classes
Price Statistics
The NADAC for LEUCOVORIN CALCIUM 5 MG TAB has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 56.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3430 per EA |
|---|---|
| All-time high | $1.0670 (May 14, 2014) |
| All-time low | $0.3019 (Feb 21, 2024) |
| 52-week high | $0.4450 |
| 52-week low | $0.3430 |
| Median price | $0.8020 |
| Average price | $0.7303 |
| Largest weekly change | +77.9% (Mar 20, 2024) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 4 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of LEUCOVORIN CALCIUM 5 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LEUCOVORIN CALCIUM 5 MG TAB, manufactured by Hikma Pharmaceuticals USA Inc., is $0.3430 per EA (NDC 00054449625), effective Aug 19, 2026.
How has the price of LEUCOVORIN CALCIUM 5 MG TAB changed over time?
Over the history we have for it, the NADAC for LEUCOVORIN CALCIUM 5 MG TAB has declined 56.3%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for LEUCOVORIN CALCIUM 5 MG TAB?
Since Nov 28, 2013, the NADAC for LEUCOVORIN CALCIUM 5 MG TAB has ranged from a low of $0.3019 (Feb 21, 2024) to a high of $1.0670 (May 14, 2014), with a median of $0.8020 per EA.
Are there cheaper alternatives to LEUCOVORIN CALCIUM 5 MG TAB?
4 manufacturers publish a NADAC-priced product with the same active ingredient and strength as LEUCOVORIN CALCIUM 5 MG TAB in a comparable dosage form, but none are currently priced below it.
Who manufactures LEUCOVORIN CALCIUM 5 MG TAB?
LEUCOVORIN CALCIUM 5 MG TAB (NDC 00054449625) is labeled by Hikma Pharmaceuticals USA Inc., and CMS classifies it as a generic product.