Product Information
LEUCOVORIN CALCIUM 25 MG TAB is a generic product labeled by Leading Pharma, LLC, priced at $1.6047 per EA under NDC 69315018725. Its NADAC has been published 274 times since Jul 7, 2021.
FDA first approved this application on Oct 22, 2020. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
25 mg/1
Manufacturer
Leading Pharma, LLCNDC
69315018725
Classification
Generic
Dosage Form
TABLET
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
LEUCOVORIN CALCIUMApproval Type
Generic (ANDA)
FDA Application
ANDA213929FDA Approved
10/22/2020
TE Code
AB
On Market Since
11/16/2020
Pharmacological Classes
Price Statistics
The NADAC for LEUCOVORIN CALCIUM 25 MG TAB has been published 274 times since Jul 7, 2021, and over the history we have for it it has declined 71.3%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.6047 per EA |
|---|---|
| All-time high | $6.2807 (May 10, 2023) |
| All-time low | $1.5005 (Dec 20, 2023) |
| 52-week high | $3.3199 |
| 52-week low | $1.6047 |
| Median price | $3.3487 |
| Average price | $3.8085 |
| Largest weekly change | -65.9% (Dec 20, 2023) |
| Weeks tracked | 274 |
| Tracking since | Jul 7, 2021 |
Generic Alternatives
No other NADAC-published product shares this drug's active ingredient and strength in a comparable dosage form. Compare the broader picture on the LEUCOVORIN CALCIUM market page.
Lowest-Cost Alternatives
No alternatives available
Related Drugs
Same classification
Continue researching this drug
Use these direct paths to move from a single NDC into the surrounding market, manufacturer, class, and trend context.
Manufacturer
Leading Pharma, LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
LEUCOVORIN CALCIUM market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Folate Analog class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of LEUCOVORIN CALCIUM 25 MG TAB?
The current National Average Drug Acquisition Cost (NADAC) for LEUCOVORIN CALCIUM 25 MG TAB, manufactured by Leading Pharma, LLC, is $1.6047 per EA (NDC 69315018725), effective Sep 30, 2026.
How has the price of LEUCOVORIN CALCIUM 25 MG TAB changed over time?
Over the history we have for it, the NADAC for LEUCOVORIN CALCIUM 25 MG TAB has declined 71.3%. It has been tracked across 274 weekly CMS publications since Jul 7, 2021.
What are the highest and lowest recorded NADAC prices for LEUCOVORIN CALCIUM 25 MG TAB?
Since Jul 7, 2021, the NADAC for LEUCOVORIN CALCIUM 25 MG TAB has ranged from a low of $1.5005 (Dec 20, 2023) to a high of $6.2807 (May 10, 2023), with a median of $3.3487 per EA.
Are there cheaper alternatives to LEUCOVORIN CALCIUM 25 MG TAB?
No other NADAC-published product currently shares the active ingredient and strength of LEUCOVORIN CALCIUM 25 MG TAB in a comparable dosage form, so no direct lower-cost alternative is listed.
Who manufactures LEUCOVORIN CALCIUM 25 MG TAB?
LEUCOVORIN CALCIUM 25 MG TAB (NDC 69315018725) is labeled by Leading Pharma, LLC, and CMS classifies it as a generic product.