Product Information
SYSTANE COMPLETE 0.6% EYE DROP is a brand product labeled by Alcon Laboratories, Inc., priced at $1.3615 per ML under NDC 00065048155. Its NADAC has been published 315 times since Jul 22, 2020.
Strength
.06 mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065048155
Classification
Brand
Dosage Form
EMULSION
Route
OPHTHALMIC
Effective Date
9/23/2026
Active Ingredients
PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
1/18/2018
Price Statistics
The NADAC for SYSTANE COMPLETE 0.6% EYE DROP has been published 315 times since Jul 22, 2020, and over the history we have for it it has risen 7.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.3615 per ML |
|---|---|
| All-time high | $1.3673 (Sep 16, 2026) |
| All-time low | $1.2336 (Mar 23, 2022) |
| 52-week high | $1.3673 |
| 52-week low | $1.3405 |
| Median price | $1.3295 |
| Average price | $1.3096 |
| Largest weekly change | +5.4% (May 17, 2023) |
| Weeks tracked | 315 |
| Tracking since | Jul 22, 2020 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 26% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
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Manufacturer
Alcon Laboratories, Inc. manufacturer profile
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Drug market
propylene glycol market comparison
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Trend hub
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Guide
Understanding NADAC pricing
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Frequently asked questions
What is the NADAC price of SYSTANE COMPLETE 0.6% EYE DROP?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE COMPLETE 0.6% EYE DROP, manufactured by Alcon Laboratories, Inc., is $1.3615 per ML (NDC 00065048155), effective Sep 30, 2026.
How has the price of SYSTANE COMPLETE 0.6% EYE DROP changed over time?
Over the history we have for it, the NADAC for SYSTANE COMPLETE 0.6% EYE DROP has risen 7.0%. It has been tracked across 315 weekly CMS publications since Jul 22, 2020.
What are the highest and lowest recorded NADAC prices for SYSTANE COMPLETE 0.6% EYE DROP?
Since Jul 22, 2020, the NADAC for SYSTANE COMPLETE 0.6% EYE DROP has ranged from a low of $1.2336 (Mar 23, 2022) to a high of $1.3673 (Sep 16, 2026), with a median of $1.3295 per ML.
Are there cheaper alternatives to SYSTANE COMPLETE 0.6% EYE DROP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SYSTANE COMPLETE 0.6% EYE DROP, is $1.0017 per ML — about 26% below SYSTANE COMPLETE 0.6% EYE DROP.
Who manufactures SYSTANE COMPLETE 0.6% EYE DROP?
SYSTANE COMPLETE 0.6% EYE DROP (NDC 00065048155) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.