Product Information
SYSTANE ULTRA 0.4-0.3% EYE DRP is a brand product labeled by Alcon Laboratories, Inc., priced at $1.0298 per ML under NDC 00065143105. Its NADAC has been published 665 times since Nov 28, 2013.
Strength
4; 3 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065143105
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
8/19/2026
Active Ingredients
POLYETHYLENE GLYCOL 400; PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
10/1/2014
Price Statistics
The NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 24.5%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0298 per ML |
|---|---|
| All-time high | $1.0311 (Aug 16, 2023) |
| All-time low | $0.8258 (Dec 18, 2013) |
| 52-week high | $1.0302 |
| 52-week low | $1.0251 |
| Median price | $0.9040 |
| Average price | $0.9309 |
| Largest weekly change | +13.0% (Jan 18, 2023) |
| Weeks tracked | 665 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 45% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SYSTANE ULTRA 0.4-0.3% EYE DRP?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE ULTRA 0.4-0.3% EYE DRP, manufactured by Alcon Laboratories, Inc., is $1.0298 per ML (NDC 00065143105), effective Aug 19, 2026.
How has the price of SYSTANE ULTRA 0.4-0.3% EYE DRP changed over time?
Over the history we have for it, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has risen 24.5%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SYSTANE ULTRA 0.4-0.3% EYE DRP?
Since Nov 28, 2013, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has ranged from a low of $0.8258 (Dec 18, 2013) to a high of $1.0311 (Aug 16, 2023), with a median of $0.9040 per ML.
Are there cheaper alternatives to SYSTANE ULTRA 0.4-0.3% EYE DRP?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SYSTANE ULTRA 0.4-0.3% EYE DRP, is $0.5616 per ML — about 45% below SYSTANE ULTRA 0.4-0.3% EYE DRP.
Who manufactures SYSTANE ULTRA 0.4-0.3% EYE DRP?
SYSTANE ULTRA 0.4-0.3% EYE DRP (NDC 00065143105) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.