Product Information
SYSTANE ULTRA 0.4-0.3% EYE DRP is a brand product labeled by Alcon Laboratories, Inc., priced at $1.0302 per ML under NDC 00065143105. Its NADAC has been published 657 times since Nov 28, 2013.
Strength
4; 3 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065143105
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
POLYETHYLENE GLYCOL 400; PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
10/1/2014
Price Statistics
The NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has been published 657 times since Nov 28, 2013, and over the history we have for it it has risen 24.6%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.0302 per ML |
|---|---|
| All-time high | $1.0311 (Aug 16, 2023) |
| All-time low | $0.8258 (Dec 18, 2013) |
| 52-week high | $1.0302 |
| 52-week low | $1.0200 |
| Median price | $0.9040 |
| Average price | $0.9297 |
| Largest weekly change | +13.0% (Jan 18, 2023) |
| Weeks tracked | 657 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 45% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of SYSTANE ULTRA 0.4-0.3% EYE DRP?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE ULTRA 0.4-0.3% EYE DRP, manufactured by Alcon Laboratories, Inc., is $1.0302 per ML (NDC 00065143105), effective Jun 24, 2026.
How has the price of SYSTANE ULTRA 0.4-0.3% EYE DRP changed over time?
Over the history we have for it, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has risen 24.6%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for SYSTANE ULTRA 0.4-0.3% EYE DRP?
Since Nov 28, 2013, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has ranged from a low of $0.8258 (Dec 18, 2013) to a high of $1.0311 (Aug 16, 2023), with a median of $0.9040 per ML.
Are there cheaper alternatives to SYSTANE ULTRA 0.4-0.3% EYE DRP?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, SYSTANE ULTRA 0.4-0.3% EYE DRP, is $0.5616 per ML — about 45% below SYSTANE ULTRA 0.4-0.3% EYE DRP.
Who manufactures SYSTANE ULTRA 0.4-0.3% EYE DRP?
SYSTANE ULTRA 0.4-0.3% EYE DRP (NDC 00065143105) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.
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