Product Information
SYSTANE ULTRA 0.4-0.3% EYE DRP is a brand product labeled by Alcon Laboratories, Inc., priced at $0.3601 per EA under NDC 00065143205. Its NADAC has been published 95 times since Apr 17, 2024.
Strength
4; 3 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065143205
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Effective Date
10/22/2025
Active Ingredients
POLYETHYLENE GLYCOL 400; PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
7/27/2009
Price Statistics
The NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has been published 95 times since Apr 17, 2024, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.3601 per EA |
|---|---|
| All-time high | $0.3636 (Jun 12, 2024) |
| All-time low | $0.3527 (Dec 18, 2024) |
| 52-week high | $0.3603 |
| 52-week low | $0.3538 |
| Median price | $0.3598 |
| Average price | $0.3590 |
| Largest weekly change | -1.8% (Nov 20, 2024) |
| Weeks tracked | 95 |
| Tracking since | Apr 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
-0.1%
3Y
N/A
5Y
N/A
All
-0.8%
Last surveyed Feb 4, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of SYSTANE ULTRA 0.4-0.3% EYE DRP?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE ULTRA 0.4-0.3% EYE DRP, manufactured by Alcon Laboratories, Inc., is $0.3601 per EA (NDC 00065143205), effective Feb 4, 2026.
How has the price of SYSTANE ULTRA 0.4-0.3% EYE DRP changed over time?
Over the history we have for it, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has held within roughly two percent of its current level. It has been tracked across 95 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for SYSTANE ULTRA 0.4-0.3% EYE DRP?
Since Apr 17, 2024, the NADAC for SYSTANE ULTRA 0.4-0.3% EYE DRP has ranged from a low of $0.3527 (Dec 18, 2024) to a high of $0.3636 (Jun 12, 2024), with a median of $0.3598 per EA.
Are there cheaper alternatives to SYSTANE ULTRA 0.4-0.3% EYE DRP?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as SYSTANE ULTRA 0.4-0.3% EYE DRP in a comparable dosage form, but none are currently priced below it.
Who manufactures SYSTANE ULTRA 0.4-0.3% EYE DRP?
SYSTANE ULTRA 0.4-0.3% EYE DRP (NDC 00065143205) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.