Product Information
SYSTANE HYDRATION PF 0.4-0.3% is a brand product labeled by Alcon Laboratories, Inc., priced at $1.1525 per ML under NDC 00065151006. Its NADAC has been published 136 times since Nov 22, 2023.
Strength
4; 3 mg/mL; mg/mL
Manufacturer
Alcon Laboratories, Inc.NDC
00065151006
Classification
Brand
Dosage Form
SOLUTION/ DROPS
Route
OPHTHALMIC
Last Updated
6/17/2026
Active Ingredients
POLYETHYLENE GLYCOL 400; PROPYLENE GLYCOLApproval Type
OTC MONOGRAPH DRUG
FDA Application
M018On Market Since
2/1/2021
Price Statistics
The NADAC for SYSTANE HYDRATION PF 0.4-0.3% has been published 136 times since Nov 22, 2023, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.1525 per ML |
|---|---|
| All-time high | $1.1993 (Feb 14, 2024) |
| All-time low | $1.1242 (Feb 21, 2024) |
| 52-week high | $1.1674 |
| 52-week low | $1.1525 |
| Median price | $1.1604 |
| Average price | $1.1597 |
| Largest weekly change | -6.3% (Feb 21, 2024) |
| Weeks tracked | 136 |
| Tracking since | Nov 22, 2023 |
Generic Alternatives
The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 51% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Frequently asked questions
What is the NADAC price of SYSTANE HYDRATION PF 0.4-0.3%?
The current National Average Drug Acquisition Cost (NADAC) for SYSTANE HYDRATION PF 0.4-0.3%, manufactured by Alcon Laboratories, Inc., is $1.1525 per ML (NDC 00065151006), effective Jun 24, 2026.
How has the price of SYSTANE HYDRATION PF 0.4-0.3% changed over time?
Over the history we have for it, the NADAC for SYSTANE HYDRATION PF 0.4-0.3% has held within roughly two percent of its current level. It has been tracked across 136 weekly CMS publications since Nov 22, 2023.
What are the highest and lowest recorded NADAC prices for SYSTANE HYDRATION PF 0.4-0.3%?
Since Nov 22, 2023, the NADAC for SYSTANE HYDRATION PF 0.4-0.3% has ranged from a low of $1.1242 (Feb 21, 2024) to a high of $1.1993 (Feb 14, 2024), with a median of $1.1604 per ML.
Are there cheaper alternatives to SYSTANE HYDRATION PF 0.4-0.3%?
Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, SYSTANE ULTRA 0.4-0.3% EYE DRP, is $0.5616 per ML — about 51% below SYSTANE HYDRATION PF 0.4-0.3%.
Who manufactures SYSTANE HYDRATION PF 0.4-0.3%?
SYSTANE HYDRATION PF 0.4-0.3% (NDC 00065151006) is labeled by Alcon Laboratories, Inc., and CMS classifies it as a brand product.
Related Drugs
Same classification