Product Information
XYLOCAINE 1%-EPI 1:100,000 is a brand product labeled by Fresenius Kabi USA, LLC, priced at $0.2721 per ML under NDC 63323048226. Its NADAC has been published 96 times since Apr 17, 2024.
FDA first approved this application before 1982. Its Orange Book therapeutic-equivalence code is AP.
Strength
.01; 10 mg/mL; mg/mL
Manufacturer
Fresenius Kabi USA, LLCNDC
63323048226
Classification
Brand
Dosage Form
INJECTION, SOLUTION
Route
INFILTRATION; PERINEURAL
Effective Date
2/1/2025
Active Ingredients
EPINEPHRINE BITARTRATE; LIDOCAINE HYDROCHLORIDE ANHYDROUSApproval Type
New Drug (NDA)
FDA Application
NDA006488FDA Approved
Before 1982
TE Code
AP
On Market Since
8/12/2010
Pharmacological Classes
Price Statistics
The NADAC for XYLOCAINE 1%-EPI 1:100,000 has been published 96 times since Apr 17, 2024, and over the history we have for it it has risen 14.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.2721 per ML |
|---|---|
| All-time high | $0.2721 (Feb 11, 2026) |
| All-time low | $0.2386 (Apr 17, 2024) |
| 52-week high | $0.2721 |
| 52-week low | $0.2721 |
| Median price | $0.2721 |
| Average price | $0.2571 |
| Largest weekly change | +14.0% (Feb 12, 2025) |
| Weeks tracked | 96 |
| Tracking since | Apr 17, 2024 |
1W
N/A
1M
N/A
3M
N/A
6M
N/A
1Y
0.0%
3Y
N/A
5Y
N/A
All
+14.0%
Last surveyed Feb 11, 2026 — this NDC no longer appears in the current weekly NADAC file.
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Frequently asked questions
What is the NADAC price of XYLOCAINE 1%-EPI 1:100,000?
The current National Average Drug Acquisition Cost (NADAC) for XYLOCAINE 1%-EPI 1:100,000, manufactured by Fresenius Kabi USA, LLC, is $0.2721 per ML (NDC 63323048226), effective Feb 11, 2026.
How has the price of XYLOCAINE 1%-EPI 1:100,000 changed over time?
Over the history we have for it, the NADAC for XYLOCAINE 1%-EPI 1:100,000 has risen 14.0%. It has been tracked across 96 weekly CMS publications since Apr 17, 2024.
What are the highest and lowest recorded NADAC prices for XYLOCAINE 1%-EPI 1:100,000?
Since Apr 17, 2024, the NADAC for XYLOCAINE 1%-EPI 1:100,000 has ranged from a low of $0.2386 (Apr 17, 2024) to a high of $0.2721 (Feb 11, 2026), with a median of $0.2721 per ML.
Are there cheaper alternatives to XYLOCAINE 1%-EPI 1:100,000?
1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as XYLOCAINE 1%-EPI 1:100,000 in a comparable dosage form, but none are currently priced below it.
Who manufactures XYLOCAINE 1%-EPI 1:100,000?
XYLOCAINE 1%-EPI 1:100,000 (NDC 63323048226) is labeled by Fresenius Kabi USA, LLC, and CMS classifies it as a brand product.