Product Information

ENTRESTO 97 MG-103 MG TABLET is a brand product labeled by Novartis Pharmaceuticals Corporation, priced at $11.5915 per EA under NDC 00078069667. Its NADAC has been published 557 times since Dec 23, 2015.

FDA first approved this application on Jul 7, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

The High Outlier badge above means this manufacturer's average price in the Sacubitril and Valsartan market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.

ENTRESTO 97 MG-103 MG TABLET

Sacubitril and Valsartan
$11.5915per EA
High Outlier

Strength

97; 103 mg/1; mg/1

NDC

00078069667

Classification

Brand

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Active Ingredients

SACUBITRIL; VALSARTAN

Approval Type

New Drug (NDA)

FDA Application

NDA207620

FDA Approved

7/7/2015

TE Code

AB

On Market Since

7/7/2015

Pharmacological Classes

Angiotensin 2 Receptor Antagonists
Angiotensin 2 Receptor Blocker
Neprilysin Inhibitor
Neprilysin Inhibitors

Price Statistics

The NADAC for ENTRESTO 97 MG-103 MG TABLET has been published 557 times since Dec 23, 2015, and over the history we have for it it has risen 93.2%. The table below summarizes its recorded NADAC range and movement.

Current price$11.5915 per EA
All-time high$11.5995 (May 13, 2026)
All-time low$5.9993 (Dec 23, 2015)
52-week high$11.5995
52-week low$11.2561
Median price$9.3141
Average price$9.0883
Largest weekly change+9.9% (Jan 23, 2019)
Weeks tracked557
Tracking sinceDec 23, 2015

Price History

1W

-0.0%

1M

-0.0%

3M

+0.0%

6M

-0.1%

1Y

+3.0%

3Y

+8.4%

5Y

+24.5%

All

+93.2%

Generic Alternatives

The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 95% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ENTRESTO 97 MG-103 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ENTRESTO 97 MG-103 MG TABLET, manufactured by Novartis Pharmaceuticals Corporation, is $11.5915 per EA (NDC 00078069667), effective Aug 19, 2026.

How has the price of ENTRESTO 97 MG-103 MG TABLET changed over time?

Over the history we have for it, the NADAC for ENTRESTO 97 MG-103 MG TABLET has risen 93.2%. It has been tracked across 557 weekly CMS publications since Dec 23, 2015.

What are the highest and lowest recorded NADAC prices for ENTRESTO 97 MG-103 MG TABLET?

Since Dec 23, 2015, the NADAC for ENTRESTO 97 MG-103 MG TABLET has ranged from a low of $5.9993 (Dec 23, 2015) to a high of $11.5995 (May 13, 2026), with a median of $9.3141 per EA.

Are there cheaper alternatives to ENTRESTO 97 MG-103 MG TABLET?

Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SACUBITRIL-VALSARTAN 97-103 MG, is $0.5932 per EA — about 95% below ENTRESTO 97 MG-103 MG TABLET.

Who manufactures ENTRESTO 97 MG-103 MG TABLET?

ENTRESTO 97 MG-103 MG TABLET (NDC 00078069667) is labeled by Novartis Pharmaceuticals Corporation, and CMS classifies it as a brand product.