Product Information
ENTRESTO 97 MG-103 MG TABLET is a brand product labeled by Novartis Pharmaceuticals Corporation, priced at $11.5887 per EA under NDC 00078069667. Its NADAC has been published 563 times since Dec 23, 2015.
FDA first approved this application on Jul 7, 2015. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
The High Outlier badge above means this manufacturer's average price in the Sacubitril and Valsartan market falls above Q3 + 1.5·IQR across all competing manufacturers. We only apply this flag in markets with four or more competitors. Full definition: glossary → outlier.
Strength
97; 103 mg/1; mg/1
Manufacturer
Novartis Pharmaceuticals CorporationNDC
00078069667
Classification
Brand
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
SACUBITRIL; VALSARTANApproval Type
New Drug (NDA)
FDA Application
NDA207620FDA Approved
7/7/2015
TE Code
AB
On Market Since
7/7/2015
Pharmacological Classes
Price Statistics
The NADAC for ENTRESTO 97 MG-103 MG TABLET has been published 563 times since Dec 23, 2015, and over the history we have for it it has risen 93.2%. The table below summarizes its recorded NADAC range and movement.
| Current price | $11.5887 per EA |
|---|---|
| All-time high | $11.5995 (May 13, 2026) |
| All-time low | $5.9993 (Dec 23, 2015) |
| 52-week high | $11.5995 |
| 52-week low | $11.2599 |
| Median price | $9.3141 |
| Average price | $9.1150 |
| Largest weekly change | +9.9% (Jan 23, 2019) |
| Weeks tracked | 563 |
| Tracking since | Dec 23, 2015 |
Generic Alternatives
The matcher finds 10 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 95% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Novartis Pharmaceuticals Corporation manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Sacubitril and Valsartan market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Angiotensin 2 Receptor Blocker class view
See how this drug behaves alongside other products in the same FDA pharmacologic class.
Trend hub
Latest market trends
Zoom back out to the weekly mover view and compare this NDC with the rest of the current NADAC release.
Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ENTRESTO 97 MG-103 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ENTRESTO 97 MG-103 MG TABLET, manufactured by Novartis Pharmaceuticals Corporation, is $11.5887 per EA (NDC 00078069667), effective Sep 30, 2026.
How has the price of ENTRESTO 97 MG-103 MG TABLET changed over time?
Over the history we have for it, the NADAC for ENTRESTO 97 MG-103 MG TABLET has risen 93.2%. It has been tracked across 563 weekly CMS publications since Dec 23, 2015.
What are the highest and lowest recorded NADAC prices for ENTRESTO 97 MG-103 MG TABLET?
Since Dec 23, 2015, the NADAC for ENTRESTO 97 MG-103 MG TABLET has ranged from a low of $5.9993 (Dec 23, 2015) to a high of $11.5995 (May 13, 2026), with a median of $9.3141 per EA.
Are there cheaper alternatives to ENTRESTO 97 MG-103 MG TABLET?
Yes. 10 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, SACUBITRIL-VALSARTAN 97-103 MG, is $0.5921 per EA — about 95% below ENTRESTO 97 MG-103 MG TABLET.
Who manufactures ENTRESTO 97 MG-103 MG TABLET?
ENTRESTO 97 MG-103 MG TABLET (NDC 00078069667) is labeled by Novartis Pharmaceuticals Corporation, and CMS classifies it as a brand product.