Product Information

GUAIFEN-CODEINE 100-10 MG/5 ML is a generic product labeled by PAI Holdings LLC, priced at $0.0645 per ML under NDC 00121077504. Its NADAC has been published 665 times since Nov 28, 2013.

GUAIFEN-CODEINE 100-10 MG/5 ML

Guaifenesin and Codeine Phosphate
$0.0645per ML
OTC
DEA Schedule CV

Strength

10; 100 mg/5mL; mg/5mL

Manufacturer

PAI Holdings LLC

NDC

00121077504

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

10/1/2006

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has been published 665 times since Nov 28, 2013, and over the history we have for it it has risen 2.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0645 per ML
All-time high$0.0773 (Jul 16, 2014)
All-time low$0.0439 (Jul 17, 2024)
52-week high$0.0647
52-week low$0.0577
Median price$0.0594
Average price$0.0594
Largest weekly change+70.5% (Jun 18, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-0.3%

1M

-0.3%

3M

+0.3%

6M

+5.2%

1Y

+8.6%

3Y

+26.7%

5Y

+10.6%

All

+2.2%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 49% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 49%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of GUAIFEN-CODEINE 100-10 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFEN-CODEINE 100-10 MG/5 ML, manufactured by PAI Holdings LLC, is $0.0645 per ML (NDC 00121077504), effective Aug 19, 2026.

How has the price of GUAIFEN-CODEINE 100-10 MG/5 ML changed over time?

Over the history we have for it, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has risen 2.2%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GUAIFEN-CODEINE 100-10 MG/5 ML?

Since Nov 28, 2013, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has ranged from a low of $0.0439 (Jul 17, 2024) to a high of $0.0773 (Jul 16, 2014), with a median of $0.0594 per ML.

Are there cheaper alternatives to GUAIFEN-CODEINE 100-10 MG/5 ML?

Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUAIFEN-CODEINE 100-10 MG/5 ML, is $0.0331 per ML — about 49% below GUAIFEN-CODEINE 100-10 MG/5 ML.

Who manufactures GUAIFEN-CODEINE 100-10 MG/5 ML?

GUAIFEN-CODEINE 100-10 MG/5 ML (NDC 00121077504) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.