Product Information
GUAIFEN-CODEINE 100-10 MG/5 ML is a generic product labeled by PAI Holdings LLC, priced at $0.0644 per ML under NDC 00121077504. Its NADAC has been published 671 times since Nov 28, 2013.
Strength
10; 100 mg/5mL; mg/5mL
Manufacturer
PAI Holdings LLCNDC
00121077504
Classification
Generic
Dosage Form
SOLUTION
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
CODEINE PHOSPHATE; GUAIFENESINApproval Type
OTC MONOGRAPH DRUG
FDA Application
M012On Market Since
10/1/2006
Pharmacological Classes
Price Statistics
The NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has been published 671 times since Nov 28, 2013, and over the history we have for it it has risen 2.0%. The table below summarizes its recorded NADAC range and movement.
| Current price | $0.0644 per ML |
|---|---|
| All-time high | $0.0773 (Jul 16, 2014) |
| All-time low | $0.0439 (Jul 17, 2024) |
| 52-week high | $0.0647 |
| 52-week low | $0.0577 |
| Median price | $0.0594 |
| Average price | $0.0594 |
| Largest weekly change | +70.5% (Jun 18, 2014) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 49% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
PAI Holdings LLC manufacturer profile
See the full portfolio, pricing trend, and other products from this labeler.
Drug market
Guaifenesin and Codeine Phosphate market comparison
Compare this molecule across participating manufacturers and inspect the broader market price spread.
Therapeutic class
Expectorant class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of GUAIFEN-CODEINE 100-10 MG/5 ML?
The current National Average Drug Acquisition Cost (NADAC) for GUAIFEN-CODEINE 100-10 MG/5 ML, manufactured by PAI Holdings LLC, is $0.0644 per ML (NDC 00121077504), effective Sep 30, 2026.
How has the price of GUAIFEN-CODEINE 100-10 MG/5 ML changed over time?
Over the history we have for it, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has risen 2.0%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for GUAIFEN-CODEINE 100-10 MG/5 ML?
Since Nov 28, 2013, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has ranged from a low of $0.0439 (Jul 17, 2024) to a high of $0.0773 (Jul 16, 2014), with a median of $0.0594 per ML.
Are there cheaper alternatives to GUAIFEN-CODEINE 100-10 MG/5 ML?
Yes. 1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, GUAIFEN-CODEINE 100-10 MG/5 ML, is $0.0327 per ML — about 49% below GUAIFEN-CODEINE 100-10 MG/5 ML.
Who manufactures GUAIFEN-CODEINE 100-10 MG/5 ML?
GUAIFEN-CODEINE 100-10 MG/5 ML (NDC 00121077504) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.