Product Information

GUAIFEN-CODEINE 100-10 MG/5 ML is a generic product labeled by PAI Holdings LLC, priced at $0.0628 per ML under NDC 00121077504. Its NADAC has been published 657 times since Nov 28, 2013.

GUAIFEN-CODEINE 100-10 MG/5 ML

Guaifenesin and Codeine Phosphate
$0.0628per ML
OTC
DEA Schedule CV

Strength

10; 100 mg/5mL; mg/5mL

Manufacturer

PAI Holdings LLC

NDC

00121077504

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Last Updated

6/17/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

10/1/2006

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has been published 657 times since Nov 28, 2013, and over the history we have for it it has held within roughly two percent of its current level. The table below summarizes its recorded NADAC range and movement.

Current price$0.0628 per ML
All-time high$0.0773 (Jul 16, 2014)
All-time low$0.0439 (Jul 17, 2024)
52-week high$0.0643
52-week low$0.0577
Median price$0.0594
Average price$0.0593
Largest weekly change+70.5% (Jun 18, 2014)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-2.3%

3M

-0.9%

6M

+6.2%

1Y

+3.4%

3Y

+30.5%

5Y

+0.4%

All

-0.6%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 49% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

Save up to 49%

1 alternative • Same active ingredient

Frequently asked questions

What is the NADAC price of GUAIFEN-CODEINE 100-10 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFEN-CODEINE 100-10 MG/5 ML, manufactured by PAI Holdings LLC, is $0.0628 per ML (NDC 00121077504), effective Jun 24, 2026.

How has the price of GUAIFEN-CODEINE 100-10 MG/5 ML changed over time?

Over the history we have for it, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has held within roughly two percent of its current level. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GUAIFEN-CODEINE 100-10 MG/5 ML?

Since Nov 28, 2013, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has ranged from a low of $0.0439 (Jul 17, 2024) to a high of $0.0773 (Jul 16, 2014), with a median of $0.0594 per ML.

Are there cheaper alternatives to GUAIFEN-CODEINE 100-10 MG/5 ML?

Yes. 1 NADAC-published product shares the same active ingredient, strength, and dosage form. The lowest-priced option, GUAIFEN-CODEINE 100-10 MG/5 ML, is $0.0323 per ML — about 49% below GUAIFEN-CODEINE 100-10 MG/5 ML.

Who manufactures GUAIFEN-CODEINE 100-10 MG/5 ML?

GUAIFEN-CODEINE 100-10 MG/5 ML (NDC 00121077504) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.