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Product Information

GUAIFEN-CODEINE 100-10 MG/5 ML is a generic product labeled by PAI Holdings LLC, priced at $0.0331 per ML under NDC 00121077516. Its NADAC has been published 665 times since Nov 28, 2013.

GUAIFEN-CODEINE 100-10 MG/5 ML

Guaifenesin and Codeine Phosphate
$0.0331per ML
OTC
DEA Schedule CV

Strength

10; 100 mg/5mL; mg/5mL

Manufacturer

PAI Holdings LLC

NDC

00121077516

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Effective Date

8/19/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

10/1/2006

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 36.1%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0331 per ML
All-time high$0.0650 (Jul 16, 2014)
All-time low$0.0250 (Dec 22, 2021)
52-week high$0.0331
52-week low$0.0311
Median price$0.0319
Average price$0.0339
Largest weekly change+95.7% (Jun 18, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

+1.8%

1M

+1.8%

3M

+2.0%

6M

+3.7%

1Y

+2.2%

3Y

+5.0%

5Y

+21.5%

All

-36.1%

Generic Alternatives

The matcher finds 1 manufacturer offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Lowest-Cost Alternatives

1 alternative • Same active ingredient

GUAIFEN-CODEINE 100-10 MG/5 ML
Generic
00121077504•PAI Holdings LLC
$0.0645
+95% more

Related Drugs

Same classification

TUSNEL DIABETIC LIQUID
Generic
54859050516•Llorens Pharmaceutical International Division
$0.0069
per ML
CHEST CONGESTION RELIEF DM SYR
Generic
00536131385•Rugby Laboratories
$0.0089
per ML
TUSNEL DIABETIC LIQUID
Generic
54859050504•Llorens Pharmaceutical International Division
$0.0111
per ML
TUSSIN DM 20-200 MG/10 ML LIQ
Generic
82568001504•Aarna USA Inc.
$0.0111
per ML
CHEST CONGESTION RELIEF SOLN
Generic
00536131485•Rugby Laboratories
$0.0112
per ML
GUAIFENESIN 100 MG/5 ML SOLN
Generic
58657050816•Method Pharmaceuticals LLC
$0.0112
per ML
GUAIFENESIN 100 MG/5 ML SOLN
Generic
81033010216•Kesin Pharma Corporation
$0.0112
per ML
TUSSIN MUCUS-CONG 200 MG/10 ML
Generic
82568001206•Aarna USA Inc.
$0.0112
per ML
GUAIFENESIN 100 MG/5 ML SOLN
Generic
83720050316•Oncor Pharmaceuticals
$0.0112
per ML
FT TUSSIN DM 200-20 MG/20 ML
Generic
70677103502•Strategic Sourcing Services LLC
$0.0114
per ML

Frequently asked questions

What is the NADAC price of GUAIFEN-CODEINE 100-10 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFEN-CODEINE 100-10 MG/5 ML, manufactured by PAI Holdings LLC, is $0.0331 per ML (NDC 00121077516), effective Aug 19, 2026.

How has the price of GUAIFEN-CODEINE 100-10 MG/5 ML changed over time?

Over the history we have for it, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has declined 36.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GUAIFEN-CODEINE 100-10 MG/5 ML?

Since Nov 28, 2013, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has ranged from a low of $0.0250 (Dec 22, 2021) to a high of $0.0650 (Jul 16, 2014), with a median of $0.0319 per ML.

Are there cheaper alternatives to GUAIFEN-CODEINE 100-10 MG/5 ML?

1 manufacturer publishes a NADAC-priced product with the same active ingredient and strength as GUAIFEN-CODEINE 100-10 MG/5 ML in a comparable dosage form, but none are currently priced below it.

Who manufactures GUAIFEN-CODEINE 100-10 MG/5 ML?

GUAIFEN-CODEINE 100-10 MG/5 ML (NDC 00121077516) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.