Product Information

GUAIFEN-CODEINE 100-10 MG/5 ML is a generic product labeled by PAI Holdings LLC, priced at $0.0323 per ML under NDC 00121077516. Its NADAC has been published 657 times since Nov 28, 2013.

GUAIFEN-CODEINE 100-10 MG/5 ML

Guaifenesin and Codeine Phosphate
$0.0323per ML
OTC
DEA Schedule CV

Strength

10; 100 mg/5mL; mg/5mL

Manufacturer

PAI Holdings LLC

NDC

00121077516

Classification

Generic

Dosage Form

SOLUTION

Route

ORAL

Last Updated

6/17/2026

Approval Type

OTC MONOGRAPH DRUG

FDA Application

M012

On Market Since

10/1/2006

Pharmacological Classes

Decreased Respiratory Secretion Viscosity
Expectorant
Full Opioid Agonists
Increased Respiratory Secretions
Opioid Agonist

Price Statistics

The NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has been published 657 times since Nov 28, 2013, and over the history we have for it it has declined 37.6%. The table below summarizes its recorded NADAC range and movement.

Current price$0.0323 per ML
All-time high$0.0650 (Jul 16, 2014)
All-time low$0.0250 (Dec 22, 2021)
52-week high$0.0339
52-week low$0.0311
Median price$0.0319
Average price$0.0339
Largest weekly change+95.7% (Jun 18, 2014)
Weeks tracked657
Tracking sinceNov 28, 2013

Price History

1W

0.0%

1M

-0.4%

3M

-0.7%

6M

+2.6%

1Y

-4.7%

3Y

+12.9%

5Y

+13.3%

All

-37.6%

Generic Alternatives

The matcher finds 1 NADAC-published product sharing this drug's active ingredient, strength, and dosage form across 1 manufacturer (up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of GUAIFEN-CODEINE 100-10 MG/5 ML?

The current National Average Drug Acquisition Cost (NADAC) for GUAIFEN-CODEINE 100-10 MG/5 ML, manufactured by PAI Holdings LLC, is $0.0323 per ML (NDC 00121077516), effective Jun 24, 2026.

How has the price of GUAIFEN-CODEINE 100-10 MG/5 ML changed over time?

Over the history we have for it, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has declined 37.6%. It has been tracked across 657 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for GUAIFEN-CODEINE 100-10 MG/5 ML?

Since Nov 28, 2013, the NADAC for GUAIFEN-CODEINE 100-10 MG/5 ML has ranged from a low of $0.0250 (Dec 22, 2021) to a high of $0.0650 (Jul 16, 2014), with a median of $0.0319 per ML.

Are there cheaper alternatives to GUAIFEN-CODEINE 100-10 MG/5 ML?

1 NADAC-published product shares the same active ingredient, strength, and dosage form as GUAIFEN-CODEINE 100-10 MG/5 ML, but none are currently priced below it.

Who manufactures GUAIFEN-CODEINE 100-10 MG/5 ML?

GUAIFEN-CODEINE 100-10 MG/5 ML (NDC 00121077516) is labeled by PAI Holdings LLC, and CMS classifies it as a generic product.