Product Information

CLOBETASOL 0.05% CREAM is a generic product labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., priced at $0.1681 per GM under NDC 00168016330. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Sep 30, 1996. Its Orange Book therapeutic-equivalence code is AB1 — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

CLOBETASOL 0.05% CREAM

clobetasol propionate
$0.1681per GM

Strength

.5 mg/g

NDC

00168016330

Classification

Generic

Dosage Form

CREAM

Route

TOPICAL

Effective Date

8/19/2026

Active Ingredients

CLOBETASOL PROPIONATE

Approval Type

Generic (ANDA)

FDA Application

ANDA074392

FDA Approved

9/30/1996

TE Code

AB1

On Market Since

9/30/1996

Pharmacological Classes

Corticosteroid Hormone Receptor Agonists
Corticosteroid

Price Statistics

The NADAC for CLOBETASOL 0.05% CREAM has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 42.2%. The table below summarizes its recorded NADAC range and movement.

Current price$0.1681 per GM
All-time high$4.7505 (Dec 10, 2014)
All-time low$0.1128 (Nov 20, 2024)
52-week high$0.1873
52-week low$0.1681
Median price$0.7076
Average price$1.1886
Largest weekly change+1563.7% (Sep 10, 2014)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-2.2%

1M

-2.2%

3M

-5.5%

6M

-3.3%

1Y

-10.2%

3Y

-24.4%

5Y

-76.2%

All

-42.2%

Generic Alternatives

The matcher finds 2 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). Switching to the cheapest would cut per-unit acquisition cost by roughly 28% at current NADAC. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of CLOBETASOL 0.05% CREAM?

The current National Average Drug Acquisition Cost (NADAC) for CLOBETASOL 0.05% CREAM, manufactured by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., is $0.1681 per GM (NDC 00168016330), effective Aug 19, 2026.

How has the price of CLOBETASOL 0.05% CREAM changed over time?

Over the history we have for it, the NADAC for CLOBETASOL 0.05% CREAM has declined 42.2%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for CLOBETASOL 0.05% CREAM?

Since Nov 28, 2013, the NADAC for CLOBETASOL 0.05% CREAM has ranged from a low of $0.1128 (Nov 20, 2024) to a high of $4.7505 (Dec 10, 2014), with a median of $0.7076 per GM.

Are there cheaper alternatives to CLOBETASOL 0.05% CREAM?

Yes. 2 manufacturers publish a NADAC-priced product with the same active ingredient and strength in a comparable dosage form. The lowest-priced option, CLOBETASOL 0.05% CREAM, is $0.1211 per GM — about 28% below CLOBETASOL 0.05% CREAM.

Who manufactures CLOBETASOL 0.05% CREAM?

CLOBETASOL 0.05% CREAM (NDC 00168016330) is labeled by E. Fougera & Co. a division of Fougera Pharmaceuticals Inc., and CMS classifies it as a generic product.