Product Information

ATOVAQUONE-PROGUANIL 250-100 MG TABLET is a generic product labeled by Prasco Laboratories, priced at $1.4777 per EA under NDC 66993006002. Its NADAC has been published 665 times since Nov 28, 2013.

FDA first approved this application on Jul 14, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.

ATOVAQUONE-PROGUANIL 250-100 MG TABLET

atovaquone and proguanil hydrochloride
$1.4777per EA

Strength

250; 100 mg/1; mg/1

NDC

66993006002

Classification

Generic

Dosage Form

TABLET, FILM COATED

Route

ORAL

Effective Date

8/19/2026

Approval Type

Authorized Generic (NDA)

FDA Application

NDA021078

FDA Approved

7/14/2000

TE Code

AB

On Market Since

7/27/2012

Pharmacological Classes

Antimalarial
Antimalarial
Antiprotozoal
Dihydrofolate Reductase Inhibitors

Price Statistics

The NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has been published 665 times since Nov 28, 2013, and over the history we have for it it has declined 71.1%. The table below summarizes its recorded NADAC range and movement.

Current price$1.4777 per EA
All-time high$5.5280 (Jan 15, 2014)
All-time low$1.2534 (Nov 20, 2024)
52-week high$1.7306
52-week low$1.4777
Median price$2.6855
Average price$3.1010
Largest weekly change+67.1% (Feb 22, 2023)
Weeks tracked665
Tracking sinceNov 28, 2013

Price History

1W

-5.1%

1M

-5.1%

3M

-5.7%

6M

-5.8%

1Y

-11.9%

3Y

-32.5%

5Y

-49.1%

All

-71.1%

Generic Alternatives

The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.

Frequently asked questions

What is the NADAC price of ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

The current National Average Drug Acquisition Cost (NADAC) for ATOVAQUONE-PROGUANIL 250-100 MG TABLET, manufactured by Prasco Laboratories, is $1.4777 per EA (NDC 66993006002), effective Aug 19, 2026.

How has the price of ATOVAQUONE-PROGUANIL 250-100 MG TABLET changed over time?

Over the history we have for it, the NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has declined 71.1%. It has been tracked across 665 weekly CMS publications since Nov 28, 2013.

What are the highest and lowest recorded NADAC prices for ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

Since Nov 28, 2013, the NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has ranged from a low of $1.2534 (Nov 20, 2024) to a high of $5.5280 (Jan 15, 2014), with a median of $2.6855 per EA.

Are there cheaper alternatives to ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ATOVAQUONE-PROGUANIL 250-100 MG TABLET in a comparable dosage form, but none are currently priced below it.

Who manufactures ATOVAQUONE-PROGUANIL 250-100 MG TABLET?

ATOVAQUONE-PROGUANIL 250-100 MG TABLET (NDC 66993006002) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.