Product Information
ATOVAQUONE-PROGUANIL 250-100 MG TABLET is a generic product labeled by Prasco Laboratories, priced at $1.4858 per EA under NDC 66993006002. Its NADAC has been published 671 times since Nov 28, 2013.
FDA first approved this application on Jul 14, 2000. Its Orange Book therapeutic-equivalence code is AB — FDA rates it therapeutically equivalent to (substitutable for) its reference product.
Strength
250; 100 mg/1; mg/1
Manufacturer
Prasco LaboratoriesNDC
66993006002
Classification
Generic
Dosage Form
TABLET, FILM COATED
Route
ORAL
Effective Date
9/23/2026
Active Ingredients
ATOVAQUONE; PROGUANIL HYDROCHLORIDEApproval Type
Authorized Generic (NDA)
FDA Application
NDA021078FDA Approved
7/14/2000
TE Code
AB
On Market Since
7/27/2012
Pharmacological Classes
Price Statistics
The NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has been published 671 times since Nov 28, 2013, and over the history we have for it it has declined 70.9%. The table below summarizes its recorded NADAC range and movement.
| Current price | $1.4858 per EA |
|---|---|
| All-time high | $5.5280 (Jan 15, 2014) |
| All-time low | $1.2534 (Nov 20, 2024) |
| 52-week high | $1.7306 |
| 52-week low | $1.4777 |
| Median price | $2.6738 |
| Average price | $3.0865 |
| Largest weekly change | +67.1% (Feb 22, 2023) |
| Weeks tracked | 671 |
| Tracking since | Nov 28, 2013 |
Generic Alternatives
The matcher finds 3 manufacturers offering a NADAC-published product with this drug's active ingredient and strength in a comparable dosage form (cheapest from each manufacturer, up to 10 shown below). None of the shown alternatives sit below the current price. These are candidates to verify clinically, not guaranteed substitutes — see our generic drug prices guide.
Related Drugs
Same classification
Continue researching this drug
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Manufacturer
Prasco Laboratories manufacturer profile
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Drug market
atovaquone and proguanil hydrochloride market comparison
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Therapeutic class
Antimalarial class view
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Trend hub
Latest market trends
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Guide
Understanding NADAC pricing
Use the explainer when you need context on how CMS publishes NADAC and how to interpret the number on this page.
Frequently asked questions
What is the NADAC price of ATOVAQUONE-PROGUANIL 250-100 MG TABLET?
The current National Average Drug Acquisition Cost (NADAC) for ATOVAQUONE-PROGUANIL 250-100 MG TABLET, manufactured by Prasco Laboratories, is $1.4858 per EA (NDC 66993006002), effective Sep 30, 2026.
How has the price of ATOVAQUONE-PROGUANIL 250-100 MG TABLET changed over time?
Over the history we have for it, the NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has declined 70.9%. It has been tracked across 671 weekly CMS publications since Nov 28, 2013.
What are the highest and lowest recorded NADAC prices for ATOVAQUONE-PROGUANIL 250-100 MG TABLET?
Since Nov 28, 2013, the NADAC for ATOVAQUONE-PROGUANIL 250-100 MG TABLET has ranged from a low of $1.2534 (Nov 20, 2024) to a high of $5.5280 (Jan 15, 2014), with a median of $2.6738 per EA.
Are there cheaper alternatives to ATOVAQUONE-PROGUANIL 250-100 MG TABLET?
3 manufacturers publish a NADAC-priced product with the same active ingredient and strength as ATOVAQUONE-PROGUANIL 250-100 MG TABLET in a comparable dosage form, but none are currently priced below it.
Who manufactures ATOVAQUONE-PROGUANIL 250-100 MG TABLET?
ATOVAQUONE-PROGUANIL 250-100 MG TABLET (NDC 66993006002) is labeled by Prasco Laboratories, and CMS classifies it as a generic product.